After conduct a review of the document, the Halogenated Organics Subcommittee unanimously concluded that the drinking water equivalent level should not be based on the non-carcinogenic endpoints of the National Toxicology Program's 1986 bioassay in male rats. It offered five reasons for this conclusion: (1) the dose of 62 mg/kg bw/day represents a no-observed-effect-level (NOEL) for cancer in male rats; (2) the endpoints of survival, body weight organs and tissues are not sufficiently sensitive; and (3) histological lesions were observed in the testes of some male rats given the 62 mg dose; and (4) to the male reproductive toxin 1,2 dibromo-3-chloropropane are sufficient evidence that the chemical may be a male reproductive toxic; and (5) the NTP bioassay was not designed to supply data for derivation of a drinking water equivalent level.