This report describes the maintenance and operation of the Organic Chemical Producers Data Base (OCPDB) from March 1979 to December 1980. During this period the OCPDB, an automated chemical information system developed for the U.S. Environmental Protection Agency, was expanded and updated by Radian Corporation. Concurrently, the data base provided users with economic, toxicity, use, and production information about more than 600 industrial organic chemical products. During the 1979-1980 maintenance task, the list of OCPDB chemical products was expanded to more than 600 from the 590 contained in the previous version of the OCPDB. Fifteen individual chemical, plastic, resin, and fiber products replaced six less-specific product groups.