Record Display for the EPA National Library Catalog


Main Title Updated mutagenicity and carcinogenicity assessment of cadmium /
Author Anderson, L. D. ; Bayard, S. ; Bayliss, D. L. ; Beliles, R. P. ; Tanchel, N. A.
CORP Author United States. Environmental Protection Agency. Office of Health and Environmental Assessment.; Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher U.S. Environmental Protection Agency, Office of Research and Development,
Year Published 1984
Report Number EPA-600/ 8-83-025b
Stock Number PB85-116150
OCLC Number 10713531
Subjects Cadmium--Toxicology ; Carcinogens ; Environmental health
Additional Subjects Cadmium--Toxicoloy ; Carcinogens ; Environmental health ; Toxicology ; Mutagens ; Assessments ; Epidemiology ; Laboratory animals ; Air pollution ; Industrial hygiene ; Exposure ; Cadmium chloride ; Malignant neoplasms ; Public health ; Risk ; Toxic substances ; Cadmium compounds ; Occupational safety and health ; Air pollution effects(Humans) ; Air pollution effects(Animals)
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EHAM  RA1231 .C3U6 1984 Region 1 Library/Boston,MA 04/29/2016
EKBD  EPA-600/8-83-025B Research Triangle Park Library/RTP, NC 03/19/2004
ELBD RPS EPA 600-8-83-025B repository copy AWBERC Library/Cincinnati,OH 03/26/2019
ESAD  EPA 600-8-83-025b Region 10 Library/Seattle,WA 09/06/2005
NTIS  PB85-116150 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Edition External review draft.
Collation viii, 174 pages : illustrations ; 28 cm
This draft document evaluates the mutagenicity and carcinogenicity of cadmium, supplementing an earlier document (Health Assessment Document for Cadmium, May 1981) which dealt with all health effects. Since the earlier document was prepared, a rat inhalation carcinogenicity study has been reported and several epidemiology and mutagenicity papers have been published. This draft document tentatively concludes that: (1) there is evidence suggesting that cadmium and certain cadmium compounds are weakly mutagenic; (2) cadmium chloride aerosol induces lung cancer in rats; (3) injected cadmium salts induce injection site sarcomas and testicular tumors in both mice and rats; (4) there is limited epidemiologic evidence that inhaled cadmium induces prostate and/or lung cancer in highly exposed workers; (5) there is no evidence that cadmium is carcinogenic via ingestion, which is a major route of human exposure, and the upper limit of potency via ingestion is at least 200 times less than via inhalation.
"Do not quote or cite." "EPA-600/ 8-83-025b." "April 1984." "Addendum to the Health Assessment Document for Cadmium (May 1981)--EPA-600/ 8-91-023."