Record Display for the EPA National Library Catalog

RECORD NUMBER: 7 OF 8

Main Title Study of the Occurrence of Metabolites of Dimethylacetamide in the Urine of Humans and Dogs, with Cover Letter dated 09/29/1995 (Sanitized).
CORP Author Du Pont de Nemours (E.I.) and Co., Wilmington, DE. Haskell Lab. for Toxicology and Industrial Medicine.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1995
Report Number OTS-86960000207S
Stock Number OTS0558347
Additional Subjects Toxicology ; Health effects ; Toxic substances ; Laboratory animals ; Pharmaco kinetics ; Mammals ; Dogs ; Dermal ; Humans ; Industrial hygiene ; CAS No 127-19-5
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Status
NTIS  OTS0558347 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 14p
Abstract
The method developed for measuring N-methylacetamide (MMAc) in the urine consisted of concentrating the urine to small volume by evaporation, extracting the concentrated urine with redistilled dichloromethane, passing the concentrated extract through alumina to remove interfering materials and Chen measuring the anide by gas chromatography. The recovery, by this procedure, of metabolite added to urine specimens averaged 85% for seven replicate samples containing 4 ppm MHnc. The details of the method are given at the end of this report.