Record Display for the EPA National Library Catalog

RECORD NUMBER: 18 OF 70

Main Title Drinking Water Criteria Document for Trichlorobenzenes.
CORP Author Environmental Protection Agency, Cincinnati, OH. Environmental Criteria and Assessment Office.
Publisher Aug 88
Year Published 1988
Report Number ECAO-CIN-D012;
Stock Number PB90-215336
Additional Subjects Potable water ; Toxicology ; Water quality ; Mutagens ; Carcinogens ; Reproduction(Biology) ; Lethal dosage ; Exposure ; Laboratory animals ; Liver ; Kidney ; Adrenal gland ; Pathology ; Benzenes/trichloro ; Pharmacokinetics ; Water pollution effects(Humans) ; Water pollution effects(Animals) ; Health hazards ; Carcinogenicity tests ; Path of pollutants ; Mutagenicity tests ; Neuroglia ; Enzyme induction ; Organ weight
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB90-215336 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 94p
Abstract
The trichlorobenzenes are a group of three chemical isomers in which three chlorine substituents have been added to a benzene ring. The trichlorobenzenes appear to enter the systemic circulation readily by inhalation, ingestion and dermal absorption; however, data were not available to quantitate the rates of these processes nor of any of the pharmacokinetic processes. The effects in mammals of acute exposure by various routes to trichlorobenzenes include local irritation, convulsions and death. Livers, kidneys, adrenals, mucous membranes and brain ganglion cells appear to be target organs with effects including edema, necrosis, fatty infiltration of livers, increased organ weights, porphyrin induction and microsomal enzyme induction.