Record Display for the EPA National Library Catalog


Main Title Ninety Day Dietary Toxicity Study in Rats.
CORP Author Monsanto Chemical Co., St. Louis, MO.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 14 Mar 1984
Year Published 1984
Report Number OTS-878213948;
Stock Number OTS-0206397
Additional Subjects Toxicity ; Rats ; Diet ; Esters ; Phosphates ; Toxic substances ; Mortality ; Food consumption ; Laboratory animals ; Body weight ; Necropsy ; Laboratory tests ; Histopathology ; Phosphate ester ; Aryl phosphates ; Nonylphenyl diphenyl phosphate ; Cumylphenyl diphenyl phosphate
Library Call Number Additional Info Location Last
NTIS  OTS-0206397 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 142p
The phosphate ester base stocks NC-220, NCP and DBPP were administered in the diet to separate groups of 5 male and female Charles River CD rats (Charles River) at a dosage of 5 mg/kg body weight/day for 90 days. A group of 5 male and female rats was administered untreated diet and served as concurrent controls. Animals were observed twice daily for mortality and toxic signs. Once each week, physical examinations were performed and body weights and food consumption were recorded. Blood was collected from all animals at the end of the study and analyzed for variations in hematological values (hematocrit, hemoglobin and erythrocyte, leucocyte, platelet and reticulocyte counts). Plasma and erythrocyte, cholinesterases were also determined at the end of the study.