Record Display for the EPA National Library Catalog


Main Title Dietary Influences on Disease Resistance Factors in Channel Catfish.
Author Blazer, V. S. ; Ankley, G. T. ; Finco-Kent, D. ;
CORP Author Georgia Cooperative Wildlife Research Unit, Athens.;Environmental Research Lab.-Duluth, MN.
Publisher c1989
Year Published 1989
Report Number EPA/600/J-89/091;
Stock Number PB90-107715
Additional Subjects Catfish ; Feeding stuffs ; Immunity ; Animal physiology ; Antibody formation ; Macrophages ; Immunization ; Reprints ; Disease resistance ; Phagocytosis ; Ictalurus punctatus ; Edwardsiella ictaluri
Library Call Number Additional Info Location Last
NTIS  PB90-107715 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 7p
The effects of diet on selected disease resistance factors were studied in channel catfish (Ictalurus punctatus). Two commercial feeds and a 'control,' laboratory-prepared diet were compared. Macrophage function (phagocytosis and intracellular killing) was used to assess nonspecific disease resistance and serum antibody was measured as an indication of specific immunity. The study measured the immune response to Edwardsiella ictaluri, a common bacterial pathogen of catfish, as well as the phagocytosis and killing of the bacteria. In the initial experiment fish were maintained on the experimental diets for 116 days, vaccinated and responses assayed 14 days later. Significant differences among the groups were observed in the phagocytic index as well as in circulating antibody. An additional study showed that even when fed the experimental diets for only 42 days there were significant differences in the ability of macrophages from both immunized and nonimmunized fish to kill E. ictaluri. (Copyright (c) 1989 Pergamon Press plc.)