Record Display for the EPA National Library Catalog


Main Title Use of Respiratory-Cardiovascular Responses of Rainbow Trout ('Salmo gairdneri') in Identifying Acute Toxicity Syndromes in Fish: Part 1. Pentachlorophenol, 2,4-Dinitrophenol, Tricaine. Methanesulfonate and 1-Octanol.
Author McKim, J. M. ; Schmieder, P. K. ; Carlson, R. W. ; Hunt, E. P. ; Niemi, G. J. ;
CORP Author Environmental Research Lab.-Duluth, MN. ;Minnesota Univ.-Duluth.
Year Published 1987
Report Number EPA/600/J-87/067;
Stock Number PB88-107065
Additional Subjects Respiration ; Cardiovascular system ; Trout ; Phosphorylation ; Toxicity ; Toxicology ; Anesthetics ; Narcosis ; Ecology ; Aquatic animals ; Reprints ; Salmo gairdneri ; Phenol/pentachloro ; Dinitrophenol
Library Call Number Additional Info Location Last
NTIS  PB88-107065 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 20p
An in vivo fish model was adapted to monitor respiratory-cardivascular responses of spinally transected rainbow trout exposed to acutely toxic aqueous concentrations of two uncouplers of oxidative phosphorylation, pentachlorophenol (PCP) and 2,4-dinitrophenol (DNP), and two narcotics, tricaine methanesulfonate (MS-222) and 1-octanol. Individual principal component analyses of the cardiovascular-respiratory responses of fish exposed to the first two principal conponents explained 68 to 76% of the variation in the 18 parameters analyzed. The general sets of responses described for these two fish acute toxicity syndromes have provided the initial information necessary to group similar responses caused by other chemicals into a fish uncoupler syndrome, a fish narcosis syndrome or some new syndrome. (Copyright (c) Environmental Toxicology and Chemistry Vol. 6, pp. 295-312, 1987, Pergamon Journals, Ltd.)