Record Display for the EPA National Library Catalog

RECORD NUMBER: 16 OF 26

Main Title Health Effects of Alpha-Emitting Particles in the Respiratory Tract.
CORP Author National Research Council, Washington, D.C. Assembly of Life Sciences.;Office of Radiation Programs, Washington, D.C.
Year Published 1976
Report Number EPA-68-01-2230; EPA/520/4-76/013;
Stock Number PB-273 111
Additional Subjects Alpha particles ; Ionizing radiation ; Radiation effects ; Respiratory system ; Radiobiology ; Lung ; Irradiation ; Radiation dosage ; Respiration ; Radiation hazards ; Pulmonary neoplasms ; Laboratory animals ; Experimental data ; Humans ; Health risks ; Cancer ; Carcinogenesis
Holdings
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NTIS  PB-273 111 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 129p
Abstract
The report presents a summary and analysis of current knowledge concerning health effects of alpha-emitting particles in the respiratory tract. The findings of the Committee were: (1) Lung cancer mortality in experimental animals can be adequately accounted for by averaging the absorbed alpha radiation dose over the entire lung; (2) Human data suggests the radiocarcinogenic sensitivity of the tracheobronchial region of the lung is greater than that of the alveolar region and the cancer risk for alpha irradiation of the alveolar region would not be underestimated by using the risk factors obtained for the tracheobronchial region; (3) Experimental evidence suggests the carcinogenic response is more a function of the amount of radioactivity in the lung than its distribution.