| Main Title |
Letter from Eastman Kodak Company to US EPA regarding Information on 5-Methyl-2-Octanone 90-Day Feeding Study. |
| CORP Author |
Tennessee Eastman Co., Kingsport.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
21 Feb 1979 |
| Year Published |
1979 |
| Report Number |
8EHQ-0279-0275; |
| Stock Number |
OTS-0200457 |
| Additional Subjects |
Toxicity ;
Solvents ;
Rats ;
Gavage ;
Laboratory tests ;
Central nervous system ;
Neuropathy ;
Dosage ;
Feeding ;
US EPA ;
Alkanes ;
Ketones ;
In vivo analysis ;
Neurotoxins ;
Metabolism ;
Adverse effects ;
MHK solvent ;
5-methyl-2-octanone ;
Eastman Kodak Company
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0200457 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
9p |
| Abstract |
The submission reports that chronic administration of MHK Solvent (5-methyl-2-octanone; 72% minimum) to rats by gavage over a 90-day period induced signs of hind-limb weakness in several of the test animals. Histologic examination of peripheral and central nervous system sections revealed giant axonal neuropathy in the MHK Solvent-dosed rats. |
