Record Display for the EPA National Library Catalog


Main Title Health assessment document for tetrachloroethylene (perchloroethylene).
Author Benignus, V. ; Chen, C. W. ; Gibb, H. J. ; Greenberg, M. M. ; Hiremath, C. B.
CORP Author United States. Environmental Protection Agency. Environmental Criteria and Assessment Office.; Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office,
Year Published 1985
Report Number EPA/600/8-82-005 F
Stock Number PB85-249704
OCLC Number 13027889
Subjects Tetrachlorides--Toxicology--United States ; Air--Pollution--Physiological effect--United States ; Air--Pollution--United States--Physiological effect
Additional Subjects Tetrachlorides--Toxicology--United States ; Air--Pollution--United States--Physiological effect ; Tetrachloroethylene ; Toxicology ; Exposure ; Laboratory animals ; Assessments ; Malignant neoplasms ; Liver ; Bacteria ; Toxic substances ; Occupational safety and health ; Pharmacokinetics ; Environmental health
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EHAM  RA1242.T45H43 1985 Region 1 Library/Boston,MA 04/29/2016
EJED  EPA 600/8-82-005F OCSPP Chemical Library/Washington,DC 01/01/1988
EKBD  EPA-600/8-82-005F Research Triangle Park Library/RTP, NC 03/19/2004
EKCD  EPA/600/8-82-005F CEMM/GEMMD Library/Gulf Breeze,FL 08/28/2018
ELBD ARCHIVE EPA 600-8-82-005F Received from HQ AWBERC Library/Cincinnati,OH 10/04/2023 DISPERSAL
EMBD  EPA/600/8-82/005F NRMRL/GWERD Library/Ada,OK 12/27/1991
ERAD  EPA 600/8-82-005f 2 copies Region 9 Library/San Francisco,CA 03/25/2016
ESAD  EPA 600-8-82-005F 2 copies Region 10 Library/Seattle,WA 06/01/2016
NTIS  PB85-249704 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 1 volume (various pagings) : illustrations ; 28 cm
Tetrachloroethylene (PCE) is a volatile solvent with important commercial applications. It has been detected in the ambient air of a variety of urban and nonurban areas of the United States. It has less frequently been detected in water but has been monitored generally at levels of 1 ppb or less. The lowest-observed-adverse-effect-level, based on central nervous system dysfunction, is about 100 ppm. Toxicity testing in experimental aminals, coupled with limited human data, suggests that long term exposure of humans to ambient levels of PCE is not likely to represent a health concern. At the current time, the teratogenic potential of PCE for humans is unknown; the mammalian animal tests performed to date do not indicate any significant teratogenic potential. Although PCE epoxide has been found to be positive with respect to mutagenicity in bacterial systems, the data on pure PCE suggest that if it is mutagenic, it is a weak mutagen. PCE has been demonstrated to induce malignant tumors of the liver in mice.
"Final report." Distributed to depository libraries in microfiche. "July 1985." Includes bibliographical references. "EPA-600/8-82-005F."