Record Display for the EPA National Library Catalog


Main Title Health assessment document for trichloroethylene : external review draft.
Author Anderson, L. D. ; Bayard, S. ; Davidson, I. W. F. ; Fowle, III, J. R. ; Gibb, H. J.
CORP Author Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office,
Year Published 1983
Report Number EPA-600/8-82-006B; EPA-600/82-006B; EPA/600/B-82/006B
Stock Number PB84-162882
OCLC Number 61370029
Subjects Trichloroethane--Toxicology--United States ; Air--Pollution--Physiological effect--United States ; Air--Pollution--United States--Physiological effect
Additional Subjects Industrial hygiene ; Degreasing ; Metals ; Air pollution ; Solvents ; Toxicology ; Laboratory animals ; Malignant neoplasms ; Urban areas ; Exposure ; Physical properties ; Chemical properties ; Metabolism ; Mutagens ; Epidemiology ; Risk ; Transport properties ; Ethylene/trichloro ; Occupational safety and health ; Indoor air pollution ; Toxic substances ; Air pollution effects(Humans) ; Cancer ; Path of pollutants ; Pharmacokinetics
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EHAM  EPA-600/8-82-006B Region 1 Library/Boston,MA 05/25/2016
ESAD  EPA 600-8-82-006B 2copies Region 10 Library/Seattle,WA 06/01/2016
NTIS  PB84-162882 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 320 pages : illustrations ; 28 cm
Trichloroethylene (TCI) is a solvent widely used in the industrial degreasing of metals. It has been detected in the ambient air of a variety of urban and non-urban areas of the United States and also, in natural and municipal waters. The weight of available evidence obtained from both animal and human data suggest that long-term exposure to environmental levels of TCI poses no serious health concern to the general population. No teratogenic potential has been demonstrated for TCI in studies conducted to date with experimental animals. With respect to the mutagenic potential of TCI, the data on pure TCI do not allow a conclusion to be drawn. If TCI is mutagenic, the available data suggest it would be a very weak, indirect mutagen. Based on available animal cancer data, the classification of TCI under the criteria of the International Agency for Research on Cancer (IARC) could either be 'sufficient' or 'limited.' Because there are no adequate epidemiologic data, the overall ranking of TCI would place it in a category in which it would be a probable human carcinogen or one that cannot be classified as to its carcinogenicity.
December 1983. "EPA-600/8-82-006B. "Review Draft - Do not cite or quote." Includes bibliographical references.