Record Display for the EPA National Library Catalog


Main Title Hazard Evaluation Division, standard evaluation procedure : guidance for evaluation of eye irritation testing.
Author Seabaugh, V. M. ; Vocci, F. J. ; Vaughan, Allen.
CORP Author United States. Environmental Protection Agency. Office of Pesticide Programs.; Environmental Protection Agency, Washington, DC. Office of Pesticide Programs.
Publisher U.S. Environmental Protection Agency, Office of Pesticide Programs,
Year Published 1988
Report Number EPA 540-09-88-105
Stock Number PB89-124572
OCLC Number 44669370
Subjects Toxicity testing--Standards ; Toxicology, Experimental
Additional Subjects Pesticides ; Guidelines ; Humans ; Animals ; Assessments ; Evaluation ; Toxicity ; Environmental health ; Eye irritants ; Standard Evaluation Procedure ; Risk assessment
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJBD  EPA 540-09-88-105 Headquarters Library/Washington,DC 06/29/2016
ELBD ARCHIVE EPA 540-09-88-105 Received from HQ AWBERC Library/Cincinnati,OH 10/04/2023
NTIS  PB89-124572 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 29 pages ; 28 cm
The Standard Evaluation Procedure for Eye Irritation Studies states the purpose and requirements, and the test is further defined in the Pesticide Assessment Guidelines (Subdivision F, Hazard Evaluation: Human and Domestic Animals, (1982, revised 1984)). Background information is given on the development of the test, animal models, scoring system, labeling, and factors affecting the results. There are discussions on objective and alternative technologies, evaluation based on weight-of-evidence, epidemiological data, and low dose and dose response studies. A tier system is presented incorporating present methods and possible future alternatives. Data Reporting Guidelines (Subdivision F, Series 81-4, Eye Irritation) are available (National Technical Information Service (NTIS), accession no. PB88-161179; EPA document no. 540/09-88-023).
"EPA-540/09-88-105." "August 1988."