Record Display for the EPA National Library Catalog


Main Title Characteristics of the U.S. EPA's Office of Pesticide Programs' Toxicity Information Databases.
Author Dearfield, K. L. ; Quest, J. A. ; Whiting, R. J. ; Stack, H. F. ; Waters, M. D. ;
CORP Author Environmental Health Research and Testing, Inc., Research Triangle Park, NC.;Health Effects Research Lab., Research Triangle Park, NC.
Publisher c1991
Year Published 1991
Report Number EPA/600/J-92/191;
Stock Number PB92-188978
Additional Subjects Data bases ; Pesticides ; Toxicity ; Health hazards ; Mutation ; Carcinogens ; Peer review ; Mutagens ; Reprints ;
Library Call Number Additional Info Location Last
NTIS  PB92-188978 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 6p
The United States Environmental Protection Agency's (USEPA's) Office of Pesticide Programs (OPP) requires that data from toxicity testing be submitted to the OPP to support the registration of pesticide chemicals. Once these data are submitted, they are entered into various toxicity data bases. The studies themselves are cataloged in an archival data base to allow retrieval of the study for review. Reviews of toxicity studies are then placed into a separate data base which can be retrieved to support a regulatory position. Toxicity information for health effects other than cancer and gene mutations from chronic exposure is reviewed through a reference dose (RfD) approach and these decisions and supporting data are entered into an RfD data base. Carcinogenicity data are reviewed by a Peer Review Process and these decisions will be entered into a newly developed data base to show the regulatory decision with supporting data. The mutagenicity data are reviewed and acceptable data are entered into the Genetic Activity Profile system to catalog and display the submitted information. These data bases contain the information used for hazard evaluations as part of the OPP review of pesticide chemicals.