Record Display for the EPA National Library Catalog


Main Title Genetic Activity Profile (GAP) Data Base.
Author Waters, M. D. ; Stack, H. F. ; Jackson, M. A. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;Environmental Health Research and Testing, Inc., Research Triangle Park, NC.
Publisher 11 Jan 91
Year Published 1991
Report Number EPA/600/D-91/049;
Stock Number PB91-177014
Additional Subjects Mutagens ; Carcinogens ; Test methods ; Microcomputers ; Dose-response relationships ; Comparative study ; Mutagenicity tests ; Carcinogenicity tests ; Data bases ; Genetic Activity Profile Database ; Weight-of-evidence ranking
Library Call Number Additional Info Location Last
NTIS  PB91-177014 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 21p
The report provides an update on the status of the genetic activity profile (GAP) data base which now consists of more than 400 chemicals. The data base is available in a personal computer software package which is described in the report. The report also describes several of the ways in which the data base and associated methodology are currently being utilized by international and U.S. governmental agencies and by industry. These include: (I) Evaluation of genetic and related effects of suspected human carcinogens, (II) Comparative evaluation of genetic activity profiles using computer-based profile matching techniques, (III) Testing and evaluation of complex mixtures, and (IV) Weight-of-evidence ranking schemes. The fundamental techniques and computer programs devised for the GAP data base may be used to develop similar data bases in genetic toxicology and in other disciplines.