||Fly Ash-Induced Changes in Hamster Tracheal Epithelium In vivo and In vitro.
Schiff, L. J. ;
Byrne, M. M. ;
Graham, J. A. ;
||IIT Research Inst., Chicago, IL.;Environmental Protection Agency, Research Triangle Park, NC.
Fly ash ;
Air pollution effects(Animals)
||Some EPA libraries have a fiche copy filed under the call number shown.
The effects of fly ash from a coal-fired power plant on tracheal epitheliun of CrRGH (SYR) Syrian golden hamsters were studied in organ cultures and after in vivo exposures. The tracheal epithelium of animals receiving 5-9 daily (5 d/wk) 3-h exposures to 2 mg fly ash per cubic meter showed large areas of basal cell hyperplasia and stratification. Surface alterations characteristic of stratified metaplasia were observed. The most characteristic findings in surface cells were broad metaplastic areas with keratin formation.