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RECORD NUMBER: 1 OF 2

Main Title Long-Term Variation Study of Blood Plasma Levels of Chloroform and Related Purgeable Compounds.
Author Pfaffenberger, Carl D. ; Peoples, Anita J. ;
CORP Author Miami Univ., FL. School of Medicine.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1982
Report Number EPA-CR-807714; EPA-600/J-82-270;
Stock Number PB83-157594
Additional Subjects Chloroform ; Blood plasma ; Exposure ; Humans ; Females ; Reprints ;
Holdings
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NTIS  PB83-157594 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 12p
Abstract
Values for circulating plasma chloroform or chloroform precursors of 25 white adult females were monitored for 6 months during Phase I of a four-phase long term variation study. The data suggested four major exposure categories. Category I (20%) had average chloroform levels < 10 ppb* and variation ranges < 10 ppb* and variation ranges < 10 ppb. Category II (24%) had average levels of 10-25 ppb and ranges of < 10 ppb. Category III (20%) had average levels of 10-25 ppb and ranges of < 20 ppb. Category IV (28%) had average chloroform levels of > 25 ppb and variation ranges > 20 ppb. Although the participants had been carefully screened to exclude incidents of occupational and recreational exposure, three subjects in category IV experienced obvious incidence of acute exposure to either chloroform or a chloroform precursor. In these situation circulating plasma chloroform levels were between 1655 ppb and 4000 ppb.