Called Part I in continuation of Parts A-B and D entered under the title: Nucleic acids, issued as volumes 12 part A, 12 part B and 21 of Methods of enzymology and Parts C and E-H entered under the title: Nucleic acids and protein synthesis, issued as volumes 20, 29, 30, 59 and 60 of Methods of enzymology. Includes bibliographical references and index.

Section I. Assays for [Class II Restriction] endonucleases -- Section II. Techniques for labeling termini -- Section III. Purification of restriction enzymes -- Section IV. Purification and properties of enzymes acting at sites with altered bases -- Section V. Endonuclease cleavage mapping techniques -- Section VI. Determination of DNA fragment sizes -- Section VII. Determination of fragment ordering -- Section VIII. Nucleotide sequencing techniques -- Section IX. Localization of functional sites on chromosomes.