The Indoor Air Quality Simulator for Personal Computers, IAQPC, was developed to address the problem of indoor air contamination. The program uses menus for the data input and to specify output. The IAQPC gives concentration profiles to cover up to 62 days for up to 6 pollutants based on information entered on a building layout, the HVAC (heating, ventilating, and air-conditioning) system parameters, and source and sink data. The building layout is chosen from six standard configurations. The building must be single-story and may have up to 20 rooms. The room volumes and the cross-sectional areas of the interconnections between the rooms (doors, cracks) may be entered. The HVAC parameters include the amount of outdoor air entering the building and the schedule of the HVAC system. Airflows for the building are calculated by the program. The Users' Guide presents an introduction to IAQPC, menu instructions, a tutorial, and brief descriptions of the meanings and reasonable inputs for the variables.