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RECORD NUMBER: 4 OF 12

Main Title DNA Adduct Research with Capillary Electrophoresis.
Author Norwood, C. B. ; Jackim, E. ; Cheer, S. ;
CORP Author Environmental Research Lab., Narragansett, RI.
Publisher c1993
Year Published 1993
Report Number EPA/600/J-93/487 ;ERLN-1437;
Stock Number PB94-130242
Additional Subjects Electrophoresis ; Deoxyribonucleic acids ; Biochemistry ; Chemical analysis ; Capillarity ; Electrodynamics ; Chromatography ; Ultraviolet detection ; Enzyme chemistry ; Nucleic acid components ; Reprints ; DNA adducts
Holdings
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NTIS  PB94-130242 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 9p
Abstract
When DNA is damaged by covalent modifications or additions of xenobiotic components, repair processes must correctly excise the offending region. Some modifications to DNA do persist and thus warrant study. The article discusses various CE techniques used in our research involving DNA adducts (modifications). CE is shown to be extremely helpful in separating various DNA components, optimizing enzyme reactions, analyzing DNA adducts, and developing adduct purification schemes. (Copyright (c) 1993 Academic Press, Inc.).