| Main Title |
Detection of Occupational Exposure to Genotoxic Agents with a Urinary Mutagen Assay. |
| Author |
Kriebel, D. ;
Commoner, B. ;
Bollinger, D. ;
Bronsdon, A. ;
Gold, J. ;
|
| CORP Author |
Queens Coll., Flushing, NY. Center for the Biology of Natural Systems.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1983 |
| Report Number |
EPA-R-804395; EPA/600/J-83/352; |
| Stock Number |
PB86-231826 |
| Additional Subjects |
Industrial medicine ;
Smoking ;
Detection ;
Exposure ;
Reprints ;
Urinalysis ;
Genotoxic agents ;
Ames test
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB86-231826 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
14p |
| Abstract |
The levels of mutagenic activity in the urine of 198 smoking and non-smoking chemical workers, coke plant workers and controls were measured using a urinary mutagen assay based on the Ames Salmonella/microsome test. Urine samples were concentrated using the non-polar resin XAD-2 eluted with methylene chloride and acetone. Activity towards Salmonella strains TA1538 and TA100 with and without microsomal preparation S-9 was measured. Regardless of occupational exposure, smokers had considerably higher urinary mutagenic activity than non-smokers on Strain TA1538 with S-9, and to a lesser extent on Strain TA100 with S-9. |
