Record Display for the EPA National Library Catalog


Main Title Aneuploidy Data Review Committee: Summary Compilation of Chemical Data Base and Evaluation of Test Methodology.
Author Dellarco, V. L. ; Mavournin, D. H. ; Waters, M. D. ;
CORP Author Oak Ridge National Lab., TN. ;Health Effects Research Lab., Research Triangle Park, NC. Genetic Toxicology Div.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Year Published 1986
Report Number EPA-68-02-3839; EPA/600/J-86/084;
Stock Number PB86-209814
Additional Subjects Toxicology ; Test methods ; Validation ; Reprints ; Aneuploidy ; Mutagenesis
Library Call Number Additional Info Location Last
NTIS  PB86-209814 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 23p
A committee of scientists was estblished by the U.S. Environmental Protection Agency to appraise the current state of aneuploidy test methodology, to compile and analyze published data on the chemical induction of aneuploidy, and to provide guidance for additional test development and validation. The committee was organized into 9 working groups, representing different eukaryotic organisms ranging from fungi to whole mammals. The Environmental Mutagen, Carcinogen, and Teratogen Information Program at Oak Ridge National Laboratory identified and provided literature to the working groups. The 9 reports were prepared by the individual working groups. The reports include: (1) descriptions of the available testing approaches and general principles to be followed for protocol development, (2) criterial for evaluating data, and (3) recommendations for future test development and basic research. The evaluated results are presented in tables.