Record Display for the EPA National Library Catalog


Main Title Allyl Chloride: The Mutagenic Activity of Its Photooxidation Products.
Author Shepson, P. B. ; Kleindienst, T. E. ; Nero, C. M. ; Hodges, D. N. ; Cupitt, L. T. ;
CORP Author Northrop Services, Inc./Environmental Sciences, Research Triangle Park, NC.;Health Effects Research Lab., Research Triangle Park, NC.
Publisher c1987
Year Published 1987
Report Number EPA-68-02-4033; EPA/600/J-87/548;
Stock Number PB91-211359
Additional Subjects Photochemistry ; Oxidation ; Allyl chloride ; Mutagens ; Salmonella typhimurium ; Smog ; Kinetics ; Bioassay ; Nitrogen oxides ; Reprints ;
Library Call Number Additional Info Location Last
NTIS  PB91-211359 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 8p
Irradiations of C3H5Cl/NOx, C3H5Cl/C2H6/NOx, and C2H6/NOx mixtures were conducted in a 22.7 cu m Teflon smog chamber, operated in a static mode. The irradiated mixtures were tested for mutagenic activity by periodically exposing Salmonella typhimurium strain TA100 to the smog chamber effluent during the irradiation. The allyl chloride photooxidation products' total mutagenic activity was found to be dramatically dependent onthe presence of Cl atom reaction products. In the absence of C2H6, which is used as a Cl atom scavenger, the observed mutagenic activity of the irradiated C3H5Cl/NOx mixture at long extent of reaction was 13 revertants per plate per hour/(ppb C3H5Cl consumed). However, when sufficient C2H6 was present to remove all Cl atoms, the observed mutagenic activity for C3H5Cl photooxidation products was 1.4 revertants per plate per hour/(ppb C3H5Cl consumed). Under conditions of excess C2H6, the mixture is approximately 30 times more mutagenic than that previously observed for the mutagenic activity of the photooxidation products of propylene, the nonchlorinated analogue of allyl chloride. The observed mutagenic activity in the presence of excess C2H6 is consistent with the total response caused by chloroacetaldehyde, a primary C3H5Cl photooxidation product. (Copyright (c) 1987 by the American Chemical Society.)