Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Histopathology and Enlargement of the Pituitary of a Teleost Exposed to the Herbicide Trifluralin.
Author Couch, J. A. ;
CORP Author Environmental Research Lab., Gulf Breeze, FL.
Year Published 1984
Report Number EPA-600/J-82-152;
Stock Number PB84-175306
Additional Subjects Herbicides ; Toxicology ; Pituitary glands ; Reprints ; Trifluralin ; Sheepshead minnows ; Cyprinodon variegatus ; Water pollution effects(Animals) ; Histopathology
Library Call Number Additional Info Location Last
NTIS  PB84-175306 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 10p
Pituitary glands of sheepshead minnows, Cyprinodon variegatus, exposed for 19 months to 1-5 micrograms/l trifluralin were significantly enlarged and possessed histopathologic characteristics (when compared to glands of controls) such as pseudocysts, congestion of blood vessels and edema. Most of the fish with enlarged pituitaries also had diffuse vertebral hyperostosis and other dysplastic vertebral changes. Several speculative mechanistic paths are suggested for the mode of the effect of trifluralin on the vertebral and pituitary tissues. Study of the form and function of pituitary glands of teleosts from natural populations might provide indications of chronic physiological stress, particularly in relation to chemical pollutant stress.