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Main Title Toxicity, Bioconcentration, and Metabolism of the Herbicide Propanil (3',4'-Dichloropropionanilide) in Freshwater Fish.
Author Call, D. J. ; Brooke, L. T. ; Kent, R. J. ; Knuth, M. L. ; Anderson, C. ;
CORP Author Wisconsin Univ.-Superior. Center for Lake Superior Environmental Studies.;Environmental Research Lab.-Duluth, MN.
Year Published 1983
Report Number EPA-R-880020; EPA-600/J-83-071;
Stock Number PB84-110253
Additional Subjects Toxicology ; Herbicides ; Chlorine organic compounds ; Lethal dosage ; Exposure ; Reprints ; Propanil ; Water pollution effects(Animals) ; Fathead minnows ; Pimephales promelas ; Rainbow trout ; Salmo gairdneri ; Propionanilide/dichloro
Library Call Number Additional Info Location Last
NTIS  PB84-110253 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 11p
Fathead minnows (Pimephales promelas) were exposed to technical grade propanil (3',4'-dichloropropionanilide) in a flow-through diluter system to determine acute lethality. LC50 values were 11.5, 10.2, 8.6, and 3.4 mg.per L at 24, 48, 96, and 192 hr, respectively. Eggs, newly hatched fry, and juvenile fish of this species were similarly exposed but at lower concentrations and for a period of 58 days. The 58-day 'no-effect' concentration was between 0.4 and 0.6 micrograms.per L, based upon the physiological parameters of length and dry weight of juvenile fish. 14C-Propanil did not bioconcentrate significantly in fathead minnows (1.6x for parent propanil in whole body). Rainbow trout (Salmo gairdneri) readily metabolized propanil, forming at least ten products. One metabolite recovered from trout bile was identified as either 3',4'-dichloro-2-hydroxypropionanilide. The technical grade propanil also contained 0.67 mg.per g of 3,3',4,4'-tetrachloroazo-benzene as a contaminant.