The report describes results from a broadly-based effort to determine the feasibility of predicting the fates of organic chemicals in diffused air, activated sludge wastewater treatment processes. The three conversion/removal mechanisms emphasized in the work were stripping, sorption on biomass, and bio-oxidation (biotransformation and mineralization). After an initial literature review and critique, separate projects were implemented to study experimental and mathematical predictive methods on each individual fate mechanism and to develop experimental and/or mathematical protocols where needed. Finally, a project was implemented to couple the mechanisms in a semi-deterministic predictive equation and to attempt initial verification for the equation in a continuous, complete and mixed laboratory activated sludge study.