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Main Title Periodic Depuration of Anthracene Metabolites by Rainbow Trout.
Author Linder, G. ; Bergman, H. L. ;
CORP Author Wyoming Univ., Laramie. Dept. of Zoology and Physiology.;Environmental Research Lab.-Duluth, MN.
Year Published 1984
Report Number EPA-R-808871; EPA/600/J-84/250;
Stock Number PB85-174076
Additional Subjects Trout ; Anthracene ; Electrolyte replenishers(Drugs) ; Exposure ; Aromatic polycyclic hydrocarbons ; Bile ; Carbon 14 ; Residues ; Periodic variations ; Hazards ; Mathematical models ; Wyoming ; Reprints ; Salmo gairdneri ; Depuration
Library Call Number Additional Info Location Last
NTIS  PB85-174076 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 11p
Rainbow trout Salmo gairdneri, statistically exposed to 36 micrograms/l anthracene (including 9-14C-anthracene), bioconcentrated the polynuclear aromatic hydrocarbon 200 times the exposure concentration over 18 hours. Then, during a 96-hour clearance period, mass-balance analysis of fish and water samples indicated that anthracene was rapidly converted to polar metabolite(s), then eliminated periodically. Maximum depuration occurred during the dark phase of a 16-hour-light: 8-hour-dark photocycle. Of the 2-3% contribution of 14C metabolite(s) to the total 14C residue, nearly half came from the bile. This periodic depuration may be circadian, although this requires confirmation by further work; to the extent it affects metabolic fate of bioconcentrated organics, periodic depuration undoubtedly contributes to differences between predicted and observed bioconcentration factors. (Copyright (c) by the American Fisheries Society 1984.)