Record Display for the EPA National Library Catalog


Main Title Standard Guide for the 'Salmonella typhimurium'/Mammalian Microsome Tests for Bacterial Mutagenicity.
Author Claxton, L. D. ; Mortelmans, K. E. ; Allen, J. ; Auletta, A. ; Nestmann, E. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1986
Report Number EPA/600/D-86/200;
Stock Number PB86-239951
Additional Subjects Bacteria ; Toxicology ; Standards ; Assaying ; Test methods ; Microsome tests ; Mutagenesis ; Salmonella tymphimurium
Library Call Number Additional Info Location Last
NTIS  PB86-239951 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 25p
Since its development by Dr. Bruce Ames and his coworkers, the Salmonella typhimurium/mammalian microsome mutagenicity assay has been used widely throughout the world. Many authors have suggested various modifications and made recommendations in regards to the assay. Although the recommendations of a panel of experts was published in 1979 by deSerres and Shelby, a committee of members of the Environmental Mutagen Society (EMS) initiated the effort in response to the encouragement by the American Society of Testing and Materials (Committe E47.09.01) and because of new developments within the field of microbial mutagenesis tests, but it is not intended for these recommendations to replace or diminish the usefulness of presently available protocols and procedures.