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Advancing Actionable Alternatives to Vertebrate Animal Testing for Chemical Safety Assessment

EPA awarded grants to five universities to research the development and use of alternative test methods and strategies that reduce, refine, and/or replace vertebrate animal testing.

Request for Applications closing date: September 25, 2018

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Selection 		Identifier Abstract Principal Investigator Institution PROJECT PERIOD Project Start Date Project End Date State
<< STAR GRANTS AND STAR CENTERS >>
1 R839501
Grant 		Instrumenting phenotypic immunological responses to toxicants that threaten human reproduction Osteen, Kevin G
Bruner-Tran, Kaylon L.
Cliffel, David
McLean, John   		Vanderbilt University Medical Center, Vanderbilt University August 2019 -
July 2022   		August 2019   July 2022   TN  
2 R839502
Grant 		Skeletal teratogenicity of industrial and environmental chemicals predicted with human pluripotent stem cells in vitro zur Nieden, Nicole I
Volz, David C.   		University of California - Riverside August 2019 -
July 2022   		August 2019   July 2022   CA  
3 R839503
Grant 		Reducing the reliance on early-life stage testing with relevance to euryhaline fishes: Development and implementation of in-vitro assays predictive of early life stage toxicity and population-level effects in Menidia beryllina Brander, Susanne M
Armbrust, Kevin
Chappell, Patrick
White, Wilson   		Oregon State University, Louisiana State University August 2019 -
July 2022   		August 2019   July 2022   OR  
4 R839504
Grant 		A Neurovascular Unit on Chip for Reducing Animals in Organophosphate Neurotoxicology Cliffel, David
May, Jody
McLaughlin, BethAnn   		Vanderbilt University, Vanderbilt University Medical Center August 2019 -
July 2020   		August 2019   July 2020   TN  
5 R839505
Grant 		Multiplexed human BrainSphere Developmental Neurotoxicity Test for Six Key Events of Neural Development Lena, Smirnova
Cynthia, Berlinicke
David, Gracias
Thomas, Hartung   		The Johns Hopkins University August 2019 -
July 2020   		August 2019   July 2020   MD  



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