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Grantee Research Project Results

Advancing Actionable Alternatives to Vertebrate Animal Testing for Chemical Safety Assessment

EPA awarded grants to five universities to research the development and use of alternative test methods and strategies that reduce, refine, and/or replace vertebrate animal testing.

Request for Applications closing date: September 25, 2018

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#	Grant Number	Abstract	Principal Investigator	Institution	Grant Amount	PROJECT PERIOD	Project Start Date	Project End Date	Extended End Date	State

<< STAR GRANTS AND STAR CENTERS >>
#	Grant Number	Abstract	Principal Investigator	Institution	Grant Amount	PROJECT PERIOD	Project Start Date	Project End Date	Extended End Date	State
1	R839501 Grant Check to remove this grant from results.	Instrumenting phenotypic immunological responses to toxicants that threaten human reproduction	Osteen, Kevin G Bruner-Tran, Kaylon L. Cliffel, David McLean, John	Vanderbilt University Medical Center, Vanderbilt University	$848,923	August 01, 2019 - July 31, 2022 (Extended to July 31, 2024)	August 01, 2019	July 31, 2022	July 31, 2024	TN
2	R839502 Grant Check to remove this grant from results.	Skeletal Teratogenicity of Industrial and Environmental Chemicals Predicted with Human Pluripotent Stem Cells in Vitro	zur Nieden, Nicole I Volz, David C.	University of California - Riverside	$849,811	August 01, 2019 - July 31, 2022 (Extended to July 31, 2024)	August 01, 2019	July 31, 2022	July 31, 2024	CA
3	R839503 Grant Check to remove this grant from results.	Reducing the reliance on early-life stage testing with relevance to euryhaline fishes: Development and implementation of in-vitro assays predictive of early life stage toxicity and population-level effects in Menidia beryllina	Brander, Susanne M Armbrust, Kevin Chappell, Patrick White, Wilson	Louisiana State University, Oregon State University	$849,988	August 01, 2019 - July 31, 2022 (Extended to July 31, 2024)	August 01, 2019	July 31, 2022	July 31, 2024
4	R839504 Grant Check to remove this grant from results.	A Neurovascular Unit on Chip for Reducing Animals in Organophosphate Neurotoxicology	Cliffel, David May, Jody McLaughlin, BethAnn Neely, M Diana	Vanderbilt University, Vanderbilt University Medical Center	$850,000	August 01, 2019 - July 31, 2022 (Extended to July 31, 2024)	August 01, 2019	July 31, 2022	July 31, 2024	TN

<< OTHER GRANTS/CENTERS >>
#	Grant Number	Abstract	Principal Investigator	Institution	Grant Amount	PROJECT PERIOD	Project Start Date	Project End Date	Extended End Date	State
5	R839505 CO-OP Check to remove this grant from results.	Multiplexed human BrainSphere Developmental Neurotoxicity Test for Six Key Events of Neural Development	Lena, Smirnova Cynthia, Berlinicke David, Gracias Romero, J. Carolina Thomas, Hartung	The Johns Hopkins University	$849,277	August 01, 2019 - July 31, 2022 (Extended to July 31, 2024)	August 01, 2019	July 31, 2022	July 31, 2024	MD

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.