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Grantee Research Project Results

Advancing Actionable Alternatives to Vertebrate Animal Testing for Chemical Safety Assessment

EPA awarded grants to five universities to research the development and use of alternative test methods and strategies that reduce, refine, and/or replace vertebrate animal testing.

Request for Applications closing date: September 25, 2018

View RFA Text

  • Abstracts
  • Publications
  • Download .csv file
 |  Help
# Grant Number Abstract Principal Investigator Institution Grant Amount PROJECT PERIOD Project Start Date Project End Date Extended End Date State
<< STAR GRANTS AND STAR CENTERS >>
# Grant Number Abstract Principal Investigator Institution Grant Amount PROJECT PERIOD Project Start Date Project End Date Extended End Date State
1 R839501
Grant



Instrumenting phenotypic immunological responses to toxicants that threaten human reproduction Osteen, Kevin G
Bruner-Tran, Kaylon L.
Cliffel, David
McLean, John  
Vanderbilt University Medical Center, Vanderbilt University $848,923   August 01, 2019 -
July 31, 2022
(Extended to July 31, 2024)  
August 01, 2019   July 31, 2022  
July 31, 2024  
TN  
2 R839502
Grant



Skeletal Teratogenicity of Industrial and Environmental Chemicals Predicted with Human Pluripotent Stem Cells in Vitro zur Nieden, Nicole I
Volz, David C.  
University of California - Riverside $849,811   August 01, 2019 -
July 31, 2022
(Extended to July 31, 2024)  
August 01, 2019   July 31, 2022  
July 31, 2024  
CA  
3 R839503
Grant



Reducing the reliance on early-life stage testing with relevance to euryhaline fishes: Development and implementation of in-vitro assays predictive of early life stage toxicity and population-level effects in Menidia beryllina Brander, Susanne M
Armbrust, Kevin
Chappell, Patrick
White, Wilson  
Louisiana State University, Oregon State University $849,988   August 01, 2019 -
July 31, 2022
(Extended to July 31, 2024)  
August 01, 2019   July 31, 2022  
July 31, 2024  
 
4 R839504
Grant



A Neurovascular Unit on Chip for Reducing Animals in Organophosphate Neurotoxicology Cliffel, David
May, Jody
McLaughlin, BethAnn
Neely, M Diana  
Vanderbilt University, Vanderbilt University Medical Center $850,000   August 01, 2019 -
July 31, 2022
(Extended to July 31, 2024)  
August 01, 2019   July 31, 2022  
July 31, 2024  
TN  
<< OTHER GRANTS/CENTERS >>
# Grant Number Abstract Principal Investigator Institution Grant Amount PROJECT PERIOD Project Start Date Project End Date Extended End Date State
5 R839505
CO-OP



Multiplexed human BrainSphere Developmental Neurotoxicity Test for Six Key Events of Neural Development Lena, Smirnova
Cynthia, Berlinicke
David, Gracias
Romero, J. Carolina
Thomas, Hartung  
The Johns Hopkins University $849,277   August 01, 2019 -
July 31, 2022
(Extended to July 31, 2024)  
August 01, 2019   July 31, 2022  
July 31, 2024  
MD  


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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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Last updated April 28, 2023
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