Grantee Research Project Results
Selected Publications Details for Grant Number R827352C001
The Chemical Toxicology of Particulate Matter
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| Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
|---|---|---|---|---|---|---|
| Journal Article | Determination of four quinones in diesel exhaust particles, SRM 1649a and atmospheric PM2.5. | AEROSOL SCIENCE AND TECHNOLOGY | Cho AK, Di Stefano E, You Y, Rodriquez CE, Schmitz DA, Kumagai Y, Miguel AH, Eiguren-Fernandez A, Kobayashi T, Avol E, Froines JR | Cho AK, Di Stefano E, You Y, Rodriquez CE, Schmitz DA, Kumagai Y, Miguel AH, Eiguren-Fernandez A, Kobayashi T, Avol E, Froines JR. Determination of four quinones in diesel exhaust particles, SRM 1649a and atmospheric PM2.5. Aerosol Science and Technology 2004;38(Suppl 1):68-81. |
R827352 (Final) R827352C001 (Final) R827352C009 (Final) R827352C013 (Final) R831861 (2004) R831861 (2005) |
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| Journal Article | Redox activity of airborne particulate matter at different sites in the Los Angeles Basin. | ENVIRONMENTAL RESEARCH | Cho AK, Sioutas C, Miguel AH, Kumagai Y, Schmitz DA, Singh M, Eiguren-Fernandez A, Froines JR | Cho AK, Sioutas C, Miguel AH, Kumagai Y, Schmitz DA, Singh M, Eiguren-Fernandez A, Froines JR. Redox activity of airborne particulate matter at different sites in the Los Angeles Basin. Environmental Research 2005;99(1):40-47. |
R827352 (Final) R827352C001 (Final) R827352C013 (Final) R827352C014 (Final) R832413C003 (2010) R832413C003 (Final) |
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| Journal Article | Effects of a single intratracheal administration of phenanthraquinone on murine lung. | JOURNAL OF APPLIED TOXICOLOGY | Hiyoshi K, Takano H, Inoue K, Ichinose T, Yanagisawa R, Tomura S, Cho AK, Froines JR, Kumagai Y | Hiyoshi K, Takano H, Inoue K, Ichinose T, Yanagisawa R, Tomura S, Cho AK, Froines JR, Kumagai Y. Effects of a single intratracheal administration of phenanthraquinone on murine lung. Journal of Applied Toxicology 2005;25(1):47-51. |
R827352 (2004) R827352 (Final) R827352C001 (Final) R832413C003 (2010) |
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| Journal Article | 1,2-Naphthoquinone activates vanilloid receptor 1 through increased protein tyrosine phosphorylation, leading to contraction of guinea pig trachea. | TOXICOLOGY AND APPLIED PHARMACOLOGY | Kikuno S, Taguchi K, Iwamoto N, Yamano S, Cho AK, Froines JR, Kumagai Y | Kikuno S, Taguchi K, Iwamoto N, Yamano S, Cho AK, Froines JR, Kumagai Y. 1,2-Naphthoquinone activates vanilloid receptor 1 through increased protein tyrosine phosphorylation, leading to contraction of guinea pig trachea. Toxicology and Applied Pharmacology 2006;210(1-2):47-54. |
R827352 (Final) R827352C001 (Final) R832413C003 (2010) |
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| Journal Article | Inhalation of concentrated ambient particulate matter near a heavily trafficked road stimulates antigen-induced airway responses in mice. | JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION | Kleinman MT, Hamade A, Meacher D, Oldham M, Sioutas C, Chakrabarti B, Stram D, Froines JR, Cho AK | Kleinman MT, Hamade A, Meacher D, Oldham M, Sioutas C, Chakrabarti B, Stram D, Froines JR, Cho AK. Inhalation of concentrated ambient particulate matter near a heavily trafficked road stimulates antigen-induced airway responses in mice. Journal of the Air & Waste Management Association 2005;55(9):1277-1288. |
R827352 (2004) R827352 (Final) R827352C001 (Final) R827352C005 (Final) R827352C014 (Final) R832413C003 (2010) |
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| Journal Article | Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage. | ENVIRONMENTAL HEALTH PERSPECTIVES | Li N, Sioutas C, Cho A, Schmitz D, Misra C, Sempf J, Wang M, Oberley T, Froines J, Nel A | Li N, Sioutas C, Cho A, Schmitz D, Misra C, Sempf J, Wang M, Oberley T, Froines J, Nel A. Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage. Environmental Health Perspectives 2003;111(4):455-460. |
R827352 (2004) R827352 (Final) R827352C001 (Final) R827352C002 (Final) R827352C014 (Final) |
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| Journal Article | Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals. | JOURNAL OF IMMUNOLOGY | Li N, Alam J, Venkatesan MI, Eiguren-Fernandez A, Schmitz D, Di Stefano E, Slaughter N, Killeen E, Wang X, Huang A, Wang M, Miguel AH, Cho A, Sioutas C, Nel AE | Li N, Alam J, Venkatesan MI, Eiguren-Fernandez A, Schmitz D, Di Stefano E, Slaughter N, Killeen E, Wang X, Huang A, Wang M, Miguel AH, Cho A, Sioutas C, Nel AE. Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals. Journal of Immunology 2004;173(5):3467-3481. |
R827352 (2004) R827352 (Final) R827352C001 (Final) R827352C002 (Final) R827352C013 (Final) R827352C014 (Final) |
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| Journal Article | Inherent redox properties of diesel exhaust particles: catalysis of the generation of reactive oxygen species by biological reductants. | TOXICOLOGICAL SCIENCES | Pan C-JG, Schmitz DA, Cho AK, Froines J, Fukuto JM | Pan C-JG, Schmitz DA, Cho AK, Froines J, Fukuto JM. Inherent redox properties of diesel exhaust particles: catalysis of the generation of reactive oxygen species by biological reductants. Toxicological Sciences 2004;81(1):225-232. |
R827352 (2004) R827352 (Final) R827352C001 (Final) |
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| Journal Article | An examination of quinone toxicity using the yeast Saccharomyces cerevisiae model system. | TOXICOLOGY | Rodriguez CE, Shinyashiki M, Froines J, Yu RC, Fukuto JM, Cho AK | Rodriguez CE, Shinyashiki M, Froines J, Yu RC, Fukuto JM, Cho AK. An examination of quinone toxicity using the yeast Saccharomyces cerevisiae model system. Toxicology 2004;201(1-3):185-196. |
R827352 (2004) R827352 (Final) R827352C001 (Final) |
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| Journal Article | The interactions of 9,10-phenanthrenequinone with glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a potential site for toxic actions. | CHEMICO-BIOLOGICAL INTERACTIONS | Rodriguez CE, Fukuto JM, Taguchi K, Froines J, Cho AK | Rodriguez CE, Fukuto JM, Taguchi K, Froines J, Cho AK. The interactions of 9,10-phenanthrenequinone with glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a potential site for toxic actions. Chemico-Biological Interactions 2005;155(1-2):97-110. |
R827352 (Final) R827352C001 (Final) R832413C003 (2010) |
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