Grantee Research Project Results
Selected Publications Details for Grant Number R828608
Development of a Physiologically Based Pharmacokinetic/ Pharmacodynamic (PBPK/PD) Model to Quantitate Biomarkers of Exposure for Organophosphate Insecticides
RFA:
Biomarkers for the Assessment of Exposure and Toxicity in Children (2000)
Other Views
- All
Publications - Selected
Publication Types - Journal
Articles - Publications Submitted
After Final Report - Redisplay this page with
Reference Title, Journal, and Author Columns - Display this Page
in RIS Format
Reference Type | Citation | Progress Report Year | Document Sources |
---|---|---|---|
Journal Article | Campbell JA, Timchalk C, Kousba AA, Wu H, Valenzuela BR, Hoppe EW. Negative ion chemical ionization mass spectrometry for the analysis of 3,5,6-trichloro-2-pyridinol in saliva of rats exposed to chlorpyrifos. Analytical Letters 2005;38(6):939-949. |
R828608 (2003) R828608 (Final) |
|
Journal Article | Kousba AA, Poet TS, Timchalk C. Characterization of the in vitro kinetic interaction of chlorpyrifos-oxon with rat salivary cholinesterase: a potential biomonitoring matrix. Toxicology 2003;188(2-3):219-232. |
R828608 (2002) R828608 (Final) |
|
Journal Article | Kousba AA, Sultatos LG, Poet TS, Timchalk C. Comparison of chlorpyrifos-oxon and paraoxon acetylcholinesterase inhibition dynamics: potential role of a peripheral binding site. Toxicological Sciences 2004;80(2):239-248. |
R828608 (2003) R828608 (Final) |
|
Journal Article | Poet TS, Wu H, Kousba AA, Timchalk C. In vitro rat hepatic and intestinal metabolism of the organophosphate pesticides chlorpyrifos and diazinon. Toxicological Sciences 2003;72(2):193-200. |
R828608 (2002) R828608 (Final) |
|
Journal Article | Timchalk C, Kousba A, Poet TS. Monte Carlo analysis of the human chlorpyrifos-oxonase (PON1) polymorphism using a physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model. Toxicology Letters 2002;135:(1-2):51-59. |
R828608 (2001) R828608 (Final) |
|
Journal Article | Timchalk C, Poet TS, Kousba AA, Campbell JA, Lin Y. Noninvasive biomonitoring approaches to determine dosimetry and risk following acute chemical exposure: analysis of lead or organophosphate insecticide in saliva. Journal of Toxicology and Environmental Health-Part A 2004;67(8-10):635-650. |
R828608 (2003) R828608 (Final) |
|
Journal Article | Timchalk C, Poet TS, Hinman MN, Busby AL, Kousba AA. Pharmacokinetic and pharmacodynamic interaction for a binary mixture of chlorpyrifos and diazinon in the rat. Toxicology and Applied Pharmacology 2005;205(1):31-42. |
R828608 (2003) R828608 (Final) |
|
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.