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Grantee Research Project Results

Selected Publications Details for Grant Number R825811

Age and Interactive Toxicity of Organophosphorus Insecticides

RFA: Issues in Human Health Risk Assessment (1997)

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Book Chapter (3)
Journal Article (10)
Reference Type Reference Title Journal Author Citation Progress Report Year Document Sources
Book Chapter The influence of age on pesticide toxicity. None Pope C Pope C. The influence of age on pesticide toxicity. In:Krieger R, ed. Handbook of Pesticide Toxicology (2nd Edition, 2-Volume Set). Volume 1. Principles. San Diego, CA: Academic Press, 2001, pp. 873-885. R825811 (Final)
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Book Chapter Nonesterase actions of anticholinesterase insecticides. Neurotoxicology Handbook Pope C, Liu J Pope C, Liu J. Nonesterase actions of anticholinesterase insecticides. In: Massaro EJ, ed. Handbook of Neurotoxicology: Volume 1. Totowa, New Jersey: Humana Press, 2002, pp. 29-43. R825811 (2000)
R825811 (Final)
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Book Chapter Age-related sensitivity to pesticides. Handbook of Pesticide Toxicology Pope CN Pope CN. Age-related sensitivity to pesticides. In: Krieger R, Doull J, Ecobichon D, Hodgson E, Reiter L, Ross J, Seiber J, Gammon D, eds. Handbook of Pesticide Toxicology, 2nd Edition, Academic Press, San Diego, CA. R825811 (2000)
not available
Journal Article In vitro effects of chlorpyrifos, parathion, methyl parathion and their oxons on cardiac muscarinic receptor binding in neonatal and adult rats. TOXICOLOGY Howard MD, Pope CN Howard MD, Pope CN. In vitro effects of chlorpyrifos, parathion, methyl parathion and their oxons on cardiac muscarinic receptor binding in neonatal and adult rats. Toxicology 2002;170(1-2):1-10. R825811 (Final)
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Journal Article In vivo interaction between chlorpyrifos and parathion in adult rats: sequence of administration can markedly influence toxic outcome. TOXICOLOGY AND APPLIED PHARMACOLOGY Karanth S, Olivier Jr K, Liu J, Pope C Karanth S, Olivier Jr. K, Liu, J, Pope C. In vivo interaction between chlorpyrifos and parathion in adult rats: sequence of administration can markedly influence toxic outcome. Toxicology and Applied Pharmacology 2001;177(3):247-255. R825811 (Final)
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  • Abstract: Science Direct
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Journal Article Comparative presynaptic neurochemical changes in rat striatum following exposure to chlorpyrifos or parathion. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A Liu J, Pope CN Liu J, Pope CN. Comparative presynaptic neurochemical changes in rat striatum following exposure to chlorpyrifos or parathion. Journal of Toxicology and Environmental Health-Part A 1998;53(7):531-544. R825811 (Final)
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Journal Article Comparative neurochemical effects of repeated methyl parathion or chlorpyrifos exposures in neonatal and adult rats. TOXICOLOGY AND APPLIED PHARMACOLOGY Liu J, Olivier K, Pope CN Liu J, Olivier K, Pope CN. Comparative neurochemical effects of repeated methyl parathion or chlorpyrifos exposures in neonatal and adult rats. Toxicology and Applied Pharmacology 1999;158(2):186-196. R825811 (Final)
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Journal Article In vitro effects of organophosphorus anticholinesterases on muscarinic receptor-mediated inhibition of acetylcholine release in rat striatum TOXICOLOGY AND APPLIED PHARMACOLOGY Liu J, Chakraborti T, Pope C Liu J, Chakraborti T, Pope C. In vitro effects of organophosphorus anticholinesterases on muscarinic receptor-mediated inhibition of acetylcholine release in rat striatum. Toxicology and Applied Pharmacology 2002;178(2):102-108. R825811 (2000)
R825811 (Final)
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Journal Article Common mechanism of toxicity: a case study of organophosphorus pesticides. TOXICOLOGICAL SCIENCES Mileson BE, Chambers JE, Chen WL, Dettbarn W, Ehrich M, Eldefrawi AT, Gaylor DW, Hamernik K, Hodgson E, Karczmar AG, Padilla S, Pope CN, Richardson RJ, Saunders DR, Sheets LP, Sultatos LG, Wallace KB Mileson BE, Chambers JE, Chen WL, Dettbarn W, Ehrich M, Eldefrawi AT, Gaylor DW, Hamernik K, Hodgson E, Karczmar AG, Padilla S, Pope CN, Richardson RJ, Saunders DR, Sheets LP, Sultatos LG, Wallace KB. Common mechanism of toxicity: a case study of organophosphorus pesticides. Toxicological Sciences 1998;41(1):8-20. R825811 (Final)
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  • Full-text: Toxicological Sciences PDF
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  • Abstract: Toxicological Sciences
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Journal Article Inhibition of forskolin-stimulated cAMP formation in vitro by paraoxon and chlorpyrifos oxon in cortical slices from neonatal, juvenile and adult rats. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY Olivier K, Liu J, Pope CN Olivier Jr. K, Liu J, Pope C. Inhibition of forskolin-stimulated cAMP formation in vitro by paraoxon and chlorpyrifos oxon in cortical slices from neonatal, juvenile, and adult rats. Journal of Biochemical and Molecular Toxicology 2001;15(5):263-269. R825811 (Final)
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Journal Article Organophosphorus pesticides: do they all have the same mechanism of toxicity? JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS Pope CN Pope CN. Organophosphorus pesticides: do they all have the same mechanism of toxicity? Journal of Toxicology and Environmental Health, Part B 1999;2(2):161-181. R825811 (Final)
  • Abstract: IngentaConnect
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Journal Article Age-related effects of chlorpyrifos on acetylcholine release in rat brain NEUROTOXICOLOGY Won YK, Liu J, Olivier Jr. K, Zheng Q, Pope CN Won YK, Liu J, Olivier Jr. K, Zheng Q, Pope CN. Age-related effects of chlorpyrifos on acetylcholine release in rat brain. Neurotoxicology 2001;22(1):39-48. R825811 (2000)
R825811 (Final)
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  • Abstract: Science Direct
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Journal Article Comparative cholinergic neurotoxicity of oral chlorpyrifos exposures in preweanling and adult rats TOXICOLOGICAL SCIENCES Zheng Q, Olivier K, Won YK, Pope CN Zheng Q, Olivier K, Won YK, Pope CN. Comparative cholinergic neurotoxicity of oral chlorpyrifos exposures in preweanling and adult rats. Toxicological Sciences 2000;55(1):124-132. R825811 (2000)
R825811 (Final)
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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