Grantee Research Project Results
Publications Details for Grant Number R825811
Age and Interactive Toxicity of Organophosphorus Insecticides
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| Reference Type | Citation | Progress Report Year | Document Sources |
|---|---|---|---|
| Abstract | Liu J, Wang G, Pope C. Differential effects of organophosphates on acetylcholine release and muscarinic autoreceptors. Toxicological Sciences 2001;60(1):242. |
R825811 (Final) |
not available |
| Abstract | Olivier K, Pope C. Comparative effects of paraoxon, chlorpyrifos oxon and muscarinic agonists on high affinity choline uptake in rat cortical or striatal synaptosomes. Toxicological Sciences 1999;48(1S):100. |
R825811 (Final) |
not available |
| Abstract | Olivier K, Pope CN. Age-related inhibition of forskolin-stimulated cAMP formation by chlorpyrifos oxon in rat cortical slices. Toxicological Sciences 2000;54(1):340. |
R825811 (2000) R825811 (Final) |
not available |
| Abstract | Olivier K, Pope CN. Age-related effects of chlorpyrifos on high affinity choline uptake in rat brain. Toxicological Sciences 2001;60(1):241. |
R825811 (Final) |
not available |
| Abstract | Stiles M, Pope CN. In vitro and in vivo effects of chlorpyrifos on cardiac muscarinic receptors. Toxicological Sciences 2000;54 (1):341. |
R825811 (2000) R825811 (Final) |
not available |
| Abstract | Won Y, Zheng Q, Liu J, Pope C. Effects of oral chlorpyrifos on cortical and striatal muscarinic autoreceptor function in neonatal, juvenile and adult rats. Toxicological Sciences 1999;48(1S):101. |
R825811 (Final) |
not available |
| Abstract | Zheng Q, Olivier K, Won Y, Pope C. Comparative cholinergic neurotoxicity of oral chlorpyrifos exposures in neonatal and adult rats. Toxicological Sciences 1999;48(1S):186. |
R825811 (Final) |
not available |
| Book Chapter | Pope C. The influence of age on pesticide toxicity. In:Krieger R, ed. Handbook of Pesticide Toxicology (2nd Edition, 2-Volume Set). Volume 1. Principles. San Diego, CA: Academic Press, 2001, pp. 873-885. |
R825811 (Final) |
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| Book Chapter | Pope C, Liu J. Nonesterase actions of anticholinesterase insecticides. In: Massaro EJ, ed. Handbook of Neurotoxicology: Volume 1. Totowa, New Jersey: Humana Press, 2002, pp. 29-43. |
R825811 (2000) R825811 (Final) |
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| Book Chapter | Pope CN. Age-related sensitivity to pesticides. In: Krieger R, Doull J, Ecobichon D, Hodgson E, Reiter L, Ross J, Seiber J, Gammon D, eds. Handbook of Pesticide Toxicology, 2nd Edition, Academic Press, San Diego, CA. |
R825811 (2000) |
not available |
| Journal Article | Howard MD, Pope CN. In vitro effects of chlorpyrifos, parathion, methyl parathion and their oxons on cardiac muscarinic receptor binding in neonatal and adult rats. Toxicology 2002;170(1-2):1-10. |
R825811 (Final) |
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| Journal Article | Karanth S, Olivier Jr. K, Liu, J, Pope C. In vivo interaction between chlorpyrifos and parathion in adult rats: sequence of administration can markedly influence toxic outcome. Toxicology and Applied Pharmacology 2001;177(3):247-255. |
R825811 (Final) |
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| Journal Article | Liu J, Pope CN. Comparative presynaptic neurochemical changes in rat striatum following exposure to chlorpyrifos or parathion. Journal of Toxicology and Environmental Health-Part A 1998;53(7):531-544. |
R825811 (Final) |
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| Journal Article | Liu J, Olivier K, Pope CN. Comparative neurochemical effects of repeated methyl parathion or chlorpyrifos exposures in neonatal and adult rats. Toxicology and Applied Pharmacology 1999;158(2):186-196. |
R825811 (Final) |
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| Journal Article | Liu J, Chakraborti T, Pope C. In vitro effects of organophosphorus anticholinesterases on muscarinic receptor-mediated inhibition of acetylcholine release in rat striatum. Toxicology and Applied Pharmacology 2002;178(2):102-108. |
R825811 (2000) R825811 (Final) |
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| Journal Article | Mileson BE, Chambers JE, Chen WL, Dettbarn W, Ehrich M, Eldefrawi AT, Gaylor DW, Hamernik K, Hodgson E, Karczmar AG, Padilla S, Pope CN, Richardson RJ, Saunders DR, Sheets LP, Sultatos LG, Wallace KB. Common mechanism of toxicity: a case study of organophosphorus pesticides. Toxicological Sciences 1998;41(1):8-20. |
R825811 (Final) |
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| Journal Article | Olivier Jr. K, Liu J, Pope C. Inhibition of forskolin-stimulated cAMP formation in vitro by paraoxon and chlorpyrifos oxon in cortical slices from neonatal, juvenile, and adult rats. Journal of Biochemical and Molecular Toxicology 2001;15(5):263-269. |
R825811 (Final) |
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| Journal Article | Pope CN. Organophosphorus pesticides: do they all have the same mechanism of toxicity? Journal of Toxicology and Environmental Health, Part B 1999;2(2):161-181. |
R825811 (Final) |
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| Journal Article | Won YK, Liu J, Olivier Jr. K, Zheng Q, Pope CN. Age-related effects of chlorpyrifos on acetylcholine release in rat brain. Neurotoxicology 2001;22(1):39-48. |
R825811 (2000) R825811 (Final) |
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| Journal Article | Zheng Q, Olivier K, Won YK, Pope CN. Comparative cholinergic neurotoxicity of oral chlorpyrifos exposures in preweanling and adult rats. Toxicological Sciences 2000;55(1):124-132. |
R825811 (2000) R825811 (Final) |
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| Meeting | Olivier, K., Liu, J. and Pope, C. (1999). Comparative effects of paraoxon, chlorpyrifos oxon and muscarinic agonists on high affinity choline uptake in rat cortical and striatal synaptosomes. Society of Toxicology annual meeting, New Orleans, LA, March 15, 1999. |
R825811 (1998) R825811 (2000) |
not available |
| Meeting | Olivier, K., Liu, J. and Pope, C. (1998). Comparative effects of paraoxon, chlorpyrifos oxon and muscarinic agonists on high affinity choline uptake in rat cortical and striatal synaptosomes. South Central Chapter/SOT annual meeting, Mississippi State University, October 23, 1998. |
R825811 (1998) R825811 (2000) |
not available |
| Meeting | Won, Y., Zheng, Q., Liu, J. and Pope, C. (1998). Effects of oral chlorpyrifos on cortical and striatal muscarinic autoreceptor function in neonatal, juvenile and adult rats. South Central Chapter/SOT annual meeting, Mississippi State University, October 23, 1998. |
R825811 (1998) R825811 (2000) |
not available |
| Presentation | Pope CN. Age-related differences in sensitivity to acute and repeated organophosphorus insecticide exposures. Presented at the Duke University Integrated Toxicology Program and Superfund Center Symposium, December 4, 2000. |
R825811 (Final) |
not available |
| Presentation | Pope CN. Age-related differences in sensitivity to acute and repeated organophosphorus insecticide exposures. Presented at an invited seminar at the University Integrated Toxicology Program and Superfund Center Symposium, December 4, 2000. |
R825811 (2000) |
not available |
| Presentation | Pope CN. Age-related differences in sensitivity to organophosphate insecticides. Presented at an invited seminar at the School of Public Health, Shanghai Medical University, Shanghai, China, April 10, 2000. |
R825811 (2000) |
not available |
| Presentation | Pope CN. Age-related differences in sensitivity to organophosphate insecticides. Presented to the School of Public Health, Shanghai Medical University, Shanghai, China, April 10, 2000. |
R825811 (Final) |
not available |
| Presentation | Pope CN. Age-related differences in sensitivity to organophosphates. Presented at the Oklahoma Center for Toxicology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, May 19, 2000. |
R825811 (Final) |
not available |
| Presentation | Pope CN. Age-related differences in sensitivity to organophosphates. Presented at an invited seminar at the Oklahoma Center for Toxicology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, May 19, 2000. |
R825811 (1998) R825811 (2000) |
not available |
| Presentation | Pope CN. Presynaptic modulation of anticholinesterase toxicity. Presented at the Life Science and Clinical Medicine 2000 Conference, Beijing, China, April 19, 2000. |
R825811 (1998) R825811 (2000) R825811 (Final) |
not available |
| Presentation | Pope CN. Toxicokinetic and toxicodynamic factors in differential sensitivity to anticholinesterases during maturation and aging. Presented at the Mayo Clinic, Rochester, MN, October 28, 2000. |
R825811 (Final) |
not available |
| Presentation | Pope CN. Toxicokinetic and toxicodynamic factors in differential sensitivity to anticholinesterases during maturation and aging. Presented at an invited seminar at the Mayo Clinic, Rochester, MN, October 28, 2000. |
R825811 (2000) |
not available |
| Presentation | Pope C. Age and sensitivity to pesticides. Presented at the School of Public Health, Sun Yat-Sen University for Medical Sciences, Guangzhou, China, October 15, 2001. |
R825811 (Final) |
not available |
| Presentation | Pope C. Age-related differences in sensitivity to chlorpyrifos are markedly incluenced by magnitude and frequency of exposure. Presented at the 7th Meeting of the International Neurotoxicology Association, Leicester, United Kingdom, July 8, 1999. |
R825811 (Final) |
not available |
| Presentation | Pope C. Are young more sensitive than adults to chlorpyrifos:animal studies. Presented at Chlorpyrifos and Human Health: Data Considerations under FQPA Meeting, Washington, DC, October 20, 1998. |
R825811 (Final) |
not available |
| Presentation | Pope C. Differential in vitro and in vivo actions of organophosphorus insecticides. Presented to Dow Agrosciences, Indianapolis, IN, June 4, 1998. |
R825811 (Final) |
not available |
| Presentation | Pope C. Differential toxicity of organophosphorus insecticides: implications for FQPA. Presented at Oklahoma State University, Stillwater, OK, May 26, 1999. |
R825811 (Final) |
not available |
| Presentation | Pope C. Influence of age on pesticide toxicity. Presented at the 3rd Chinese Society of Toxicology Meeting, Nanjing, China, October 17, 2001. |
R825811 (Final) |
not available |
| Presentation | Pope C. Influence of age on pesticide toxicity. Presented to the Department of Zoology, Oklahoma State University, Stillwater, OK, September 21, 2001. |
R825811 (Final) |
not available |
| Presentation | Pope C. Presynaptic modulation of organophosphate neurotoxicity. Presented at the Medical College of Virginia, Richmond, VA, January 28, 1999. |
R825811 (Final) |
not available |
| Presentation | Pope C. Presynaptic modulation of organophosphate neurotoxicity. Presented at the University of Kentucky, Lexington, KY, February 9, 1999. |
R825811 (Final) |
not available |
| Presentation | Pope C. Toxicokinetic and toxicodynamic factors in differential sensitivity to organophosphorus insecticides during maturation and aging. Presented to the Department of Entomology and Plant Pathology, Oklahoma State University, Stillwater, OK, February 7, 2001. |
R825811 (Final) |
not available |
| Presentation | Pope C. Toxicokinetic and toxicodynamic factors in differential sensitivity to organophosphorus insecticides. Presented at the International Neurotoxicology Association Meeting, Estoril, Portugal, June 13, 2001. |
R825811 (Final) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.