Grantee Research Project Results
Selected Publications Details for Grant Number R826300
Dioxin and Steroid Regulation in an Endometriosis Model
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Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
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Book Chapter | Interleukin-1α opposes suppression of human endometrial matrix metalloproteinases by progesterone in a model of experimental endometriosis. | None | Bruner KL, Keller NR, Osteen KG | Bruner KL, Keller NK, Osteen KG. Interleukin-1α opposes suppression of human endometrial matrix metalloproteinases by progesterone in a model of experimental endometriosis. In: Lemay A, Maheux R, eds. Understanding and Managing Endometriosis: Advances in Research and Practice. New York, NY: Parthenon Publishing, 1999, pp. 123-130. |
R826300 (1999) R826300 (Final) |
not available |
Journal Article | Effect of TCDD exposure on CYP1A1 and CYP1B1 expression in explant cultures of human endometrium. | TOXICOLOGICAL SCIENCES | Bofinger DP, Feng L, Chi L-H, Love J, Stephen FD, Sutter TR, Osteen KG, Costich TG, Batt RE, Koury ST, Olson JR | Bofinger DP, Feng L, Chi L-H, Love J, Stephen FD, Sutter TR, Osteen KG, Costich TG, Batt RE, Koury ST, Olson JR. Effect of TCDD exposure on CYP1A1 and CYP1B1 expression in explant cultures of human endometrium. Toxicological Sciences 2001;62(2):299-314. |
R826300 (Final) |
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Journal Article | Progesterone and transforming growth factor-β coordinately regulate suppression of endometrial matrix metalloproteinases in a model of experimental endometriosis | STEROIDS | Bruner KL, Eisenberg E, Gorstein F, Osteen KG | Bruner KL, Eisenberg E, Gorstein F, Osteen KG. Progesterone and transforming growth factor-β coordinately regulate suppression of endometrial matrix metalloproteinases in a model of experimental endometriosis. Steroids 1999;64(9):648-653. |
R826300 (1999) R826300 (Final) |
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Journal Article | The potential role of environmental toxins in the pathophysiology of endometriosis | OBSTETRIC AND GYNECOLOGIC INVESTIGATION | Bruner-Tran KL, Rier SE, Eisenberg E, Osteen KG | Bruner-Tran KL, Rier SE, Eisenberg E, Osteen KG. The potential role of environmental toxins in the pathophysiology of endometriosis. Obstetric and Gynecologic Investigation 1999;48(Suppl 1):45-56. |
R826300 (1999) R826300 (Final) |
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Journal Article | Steroid and cytokine regulation of matrix metalloproteinase expression in endometriosis and the establishment of experimental endometriosis in nude mice. | JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM | Bruner-Tran KL, Eisenberg E, Yeaman GR, Anderson TA, McBean J, Osteen KG | Bruner-Tran KL, Eisenberg E, Yeaman GR, Anderson TA, McBean J, Osteen KG. Steroid and cytokine regulation of matrix metalloproteinase expression in endometriosis and the establishment of experimental endometriosis in nude mice. Journal of Clinical Endocrinology and Metabolism 2002;87(10):4782-4791. |
R826300 (Final) |
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Journal Article | Exposure to the environmental endocrine disruptor TCDD and human reproductive dysfunction: translating lessons from murine models. | None | Bruner-Tran KL, Gnecco J, Ding T, Glore DR, Pensabene V, Osteen KG | Bruner-Tran KL, Gnecco J, Ding T, Glore DR, Pensabene V, Osteen KG. Exposure to the environmental endocrine disruptor TCDD and human reproductive dysfunction: translating lessons from murine models. Reproductive Toxicology 2017;68:59-71. |
R826300 (Final) R835736 (2015) R835736 (2016) R835736 (2017) R835736C003 (2016) R835736C003 (2017) R835736C003 (2018) |
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Journal Article | Cyclic changes in the matrix metalloproteinase system in the ovary and uterus. | BIOLOGY OF REPRODUCTION | Curry Jr. TE, Osteen KG | Curry Jr. TE, Osteen KG. Cyclic changes in the matrix metalloproteinase system in the ovary and uterus. Biology of Reproduction 2001;64(5):1285-1296. |
R826300 (Final) |
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Journal Article | Reduced expression of progesterone receptor-B in the endometrium of women with endometriosis and in cocultures of endometrial cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin | FERTILITY AND STERILITY | Igarashi TM, Bruner-Tran KL, Yeaman GR, Lessey BA, Edwards DP, Eisenberg E, Osteen KG | Igarashi TM, Bruner-Tran KL, Yeaman GR, Lessey BA, Edwards DP, Eisenberg E, Osteen KG. Reduced expression of progesterone receptor-B in the endometrium of women with endometriosis and in cocultures of endometrial cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Fertility and Sterility 2005;84(1):67-74. |
R826300 (Final) |
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Journal Article | Paracrine regulation of matrix metalloproteinase expression in the normal human endometrium. | GYNECOLOGIC AND OBSTETRIC INVESTIGATION | Osteen KG, Keller NR, Feltus FA, Melner MH | Osteen KG, Keller NR, Feltus FA, Melner MH. Paracrine regulation of matrix metalloproteinase expression in the normal human endometrium. Gynecologic and Obstetric Investigation 1999;48(Suppl 1):2-13. |
R826300 (1999) R826300 (Final) |
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.