Grantee Research Project Results
Publications Details for Grant Number R826408
Mechanisms of Carcinogenesis of the Fungicide and Rat Bladder Carcinogen o-Phenylphenol
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| Reference Type | Citation | Progress Report Year | Document Sources |
|---|---|---|---|
| Abstract | Balakrishnan S, Hasegawa L, Rupa DS, Tadi-Uppala P, Eastmond DA. Detection of hyperdiploidy in bladder epithelial cells of rats treated with ortho-phenylphenol using fluorescence in situ hybridization. Environmental and Molecular Mutagenesis 1999;33:13. |
R826408 (1999) R826408 (Final) |
not available |
| Abstract | Balakrishnan S, Eastmond DA. Cytotoxicity studies into the role of pH-dependent autoxidation of phenylhydroquinone in ortho-phenylphenol induced urinary bladder carcinogenesis in male F344 rats. Environmental and Molecular Mutagenesis 2000;35:11. |
R826408 (1999) R826408 (Final) |
not available |
| Abstract | Balakrishnan S, Payawal JH, Hasegawa LS, Schuler MJ, Eastmond DA. Detection of hyperdiploidy in rat interphase hepatocytes following treatment in vivo with vinblastine sulfate using fluorescence in situ hybridization (FISH). Environmental and Molecular Mutagenesis 2001;37(S32):20. |
R826408 (Final) |
not available |
| Abstract | Balakrishnan S, Eastmond DA. Studies in the mechanism(s) of ortho-phenylphenol induced bladder carcinogenesis in F344 rats. Mutation Research 2001;483(1):S186. |
R826408 (Final) |
not available |
| Abstract | Balakrishnan S, Eastmond DA. Cellular and genetic studies into the role of pH-dependent autoxidation of phenylhydroquinone in ortho-phenylphenol induced bladder carcinogenesis in male F344 rats. Toxicologist Supplement 2002;66(1-S):LB6. |
R826408 (Final) |
not available |
| Book Chapter | Eastmond DA, Balakrishnan S. Genetic toxicity of pesticides. In: Krieger R, Doull J, Ecobichon D, Hodgson E, Reiter L, Ross J, Seiber J, Gammon D, eds. Handbook of Pesticide Toxicology. San Diego, CA: Academic Press, 2nd Ed., 2001, pp. 747-767. |
R826408 (Final) |
not available |
| Journal Article | Balakrishnan S, Payawal J, Schuler M, Hasegawa L, Eastmond DA. Enhancing the in vitro and in vivo detection of aneuploidy by fluorescence in situ hybridization with the use of bromodeoxyuridine as a proliferation marker. Mutation Research. 2002, Volume: 521, Number: 1-2 (NOV 26), Page: 81-89. |
R826408 (Final) |
not available |
| Journal Article | Balakrishnan S, Uppala PT, Rupa DS, Hasegawa L, Eastmond DA. Detection of micronuclei, cell proliferation, and hyperdiploidy in bladder epithelial cells of rats treated with ortho-phenylphenol. Mutagenesis 2002;17(1):89-93. |
R826408 (Final) |
not available |
| Journal Article | Bielawski D, Ostrea Jr. E, Posecion Jr. N, Corrion M, Seagraves J. Detection of several classes of pesticides and metabolites in meconium by gas chromatography/mass spectrometry. Chromatographia 2005;62(11-12):623-629. |
R826408 (Final) R829395 (2004) R829395 (Final) |
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| Journal Article | Kwok ESC, Buchholz BA, Vogel JS, Turteltaub KW, Eastmond DA. Dose-dependent binding of ortho-phenylphenol (OPP) to protein but not DNA in the urinary bladder of male F344 rats. Toxicology and Applied Pharmacology 1999;159(1):18-24. |
R826408 (1999) R826408 (Final) |
|
| Presentation | Balakrishnan S, Eastmond DA. Cellular and genetic studies into the role of pH-dependent autoxidation of phenylhydroquinone in ortho-phenylphenol induced bladder carcinogenesis in male F344 rats. Presented at the Society of Toxicology Meeting, Nashville, TN, March 18-20, 2002. |
R826408 (Final) |
not available |
| Presentation | Balakrishnan S, Eastmond DA. Cytotoxicity studies into the role of pH-dependent autoxidation of phenylhydroquinone in ortho-phenylphenol induced urinary bladder carcinogenesis in male F344 rats. Presented at the Annual Environmental Mutagen Society Meeting, New Orleans, LA, April 8-13, 2000. |
R826408 (1999) R826408 (Final) |
not available |
| Presentation | Balakrishnan S, Hasegawa L, Rupa DS, Tadi-Uppala P, Eastmond DA. Detection of hyperdiploidy in bladder epithelial cells of rats treated with ortho-phenylphenol using fluorescence in situ hybridization. Presented at the Annual Environmental Mutagen Society Meeting, Washington, DC, March 29, 1999. |
R826408 (1999) R826408 (Final) |
not available |
| Presentation | Balakrishnan S, Payawal JH, Hasegawa LS, Schuler MJ, Eastmond DA. Detection of hyperdiploidy in rat interphase hepatocytes following treatment in vivo with vinblastine sulfate using fluorescence in situ hybridization (FISH). Presented at the Annual Environmental Mutagen Society Meeting, San Diego, CA, March 16-21, 2001. |
R826408 (Final) |
not available |
| Presentation | Balakrishnan S, Eastmond DA. Studies in the mechanism(s) of ortho-phenylphenol induced bladder carcinogenesis in F344 rats. Presented at the 8th International Conference on Environmental Mutagens, Shizuoka, Japan, October 21-26, 2001. |
R826408 (Final) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.