Grantee Research Project Results
Publications Details for Grant Number R824758
Role of Developmental Neurotoxicology in Autism
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Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
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Abstract | Valproic acid-induced brain damage in rats as a model for autism. | TERATOLOGY | Ingram JL, Tisdale B, Rodier PM | Ingram JL, Tisdale B, Rodier PM. Valproic acid-induced brain damage in rats as a model for autism. Teratology 1995;51:169. |
R824758 (Final) |
not available |
Abstract | Mutations in HoxA-1 are associated with some cases of autism. | TERATOLOGY | Ingram JL, Stodgell CJ, Kern JR, Hyman SL, Figlewicz DA, Rodier PM | Ingram JL, Stodgell CJ, Kern JR, Hyman SL, Figlewicz DA, Rodier PM. Mutations in HoxA-1 are associated with some cases of autism. Teratology 1997;55:50. |
R824758 (Final) |
not available |
Abstract | Valproic acid alters expression of HoxA1 in rat embryos: a mechanism of teratogenesis? | TERATOLOGY | Ingram JL, Rodier PM | Ingram JL, Rodier PM. Valproic acid alters expression of HoxA1 in rat embryos:a mechanism of teratogenesis? Teratology 1998;57:191. |
R824758 (Final) |
not available |
Abstract | Phenotype predicts the genotype of brain stem injury in autism. | TERATOLOGY | Rodier PM, Ingram JL, Hyman SL, Figlewicz DA | Rodier PM, Ingram JL, Hyman SL, Figlewicz DA. Phenotype predicts the genotype of brain stem injury in autism. Teratology 1997;55:32. |
R824758 (Final) |
not available |
Abstract | Embryology of autism. | FASEB JOURNAL | Rodier PM | Rodier PM. Embryology of autism. FASEB Journal 1998;12:2070. |
R824758 (Final) |
not available |
Abstract | Association of an alternate form of the homeotic gene HoxB1 with cases of familial autism spectrum disorder. | TERATOLOGY | Stodgell CJ, Hyman SL, Knauber LK, Rodier PM | Stodgell CJ, Hyman SL, Knauber LK, Rodier PM. Association of an alternate form of the homeotic gene HoxB1 with cases of familial autism spectrum disorder. Teratology 1998;57:192. |
R824758 (Final) |
not available |
Book Chapter | Neuroteratology of autism. | None | Rodier PM | Rodier PM. Neuroteratology of autism. In:Slikker Jr W, Chang LW, eds. Handbook of Developmental Neurotoxicology. San Diego, CA:Academic Press, 1998, Chapter 38, pp. 661-672. |
R824758 (Final) R831725 (2007) R831725 (2009) |
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Journal Article | Discovery of allelic variants of HOXA1 and HOXB1: genetic susceptibility to autism spectrum disorders. | NATURE GENETICS | Ingram JL, Stodgell CJ, Hyman SL, Figlewicz DA, Weitkamp LR, Rodier PM | Ingram JL, Stodgell CJ, Hyman SL, Figlewicz DA, Weitkamp LR, Rodier PM. Discovery of allelic variants of HOXA1 and HOXB1: genetic susceptibility to autism spectrum disorders. Teratology 2000;62(6):393-405. |
R824758 (Final) |
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Journal Article | Prenatal exposure of rats to valproic acid reproduces the cerebellar anomalies associated with autism. | None | Ingram JL, Peckham SM, Tisdale B, Rodier PM | Ingram JL, Peckham SM, Tisdale B, Rodier PM. Prenatal exposure of rats to valproic acid reproduces the cerebellar anomalies associated with autism. Neurotoxicology and Teratology 2000;22(3):319-324. |
R824758 (Final) |
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Journal Article | Developing brain as a target of toxicity. | ENVIRONMENTAL HEALTH PERSPECTIVES | Rodier PM | Rodier PM. Developing brain as a target of toxicity. Environmental Health Perspectives 1995;103(Suppl 6):73-76. |
R824758 (Final) |
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Journal Article | Embryological origin for autism: developmental anomalies of the cranial nerve motor nuclei. | JOURNAL OF COMPARATIVE NEUROLOGY | Rodier PM, Ingram JL, Tisdale B, Nelson S, Romano J | Rodier PM, Ingram JL, Tisdale B, Nelson S, Romano J. Embryological origin for autism: developmental anomalies of the cranial nerve motor nuclei. Journal of Comparative Neurology 1996;370(2):247-261. |
R824758 (Final) |
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Journal Article | Animal model of autism based on developmental data. | MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS | Rodier PM | Rodier PM. Animal model of autism based on developmental data. Mental Retardation and Developmental Disabilities Research Reviews 1996;2(4):249-256. |
R824758 (Final) |
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Journal Article | Linking etiologies in humans and animal models: studies of autism. | REPRODUCTIVE TOXICOLOGY | Rodier PM, Ingram JL, Tisdale B, Croog VJ | Rodier PM, Ingram JL, Tisdale B, Croog VJ. Linking etiologies in humans and animal models: studies of autism. Reproductive Toxicology 1997;11(2-3):417-422. |
R824758 (Final) |
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Journal Article | Minor malformations and physical measures in autism: data from Nova Scotia. | TERATOLOGY | Rodier PM, Bryson SE, Welsh JP | Rodier PM, Bryson SE, Welsh JP. Minor malformations and physical measures in autism: data from Nova Scotia. Teratology 1997;55(5):319-325. |
R824758 (Final) |
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Journal Article | Early environmental factors in autism. | MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS | Rodier PM, Hyman SL | Rodier PM, Hyman SL. Early environmental factors in autism. Mental Retardation and Developmental Disabilities Research Reviews 1998;4(2):121-128. |
R824758 (Final) |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.