Grantee Research Project Results
Publications Details for Grant Number R828035
Infectivity and Virulence of Cryptosporidium Genotype H Oocysts in Healthy Adult Volunteers
Other Views
- All
Publications - Selected
Publication Types - Journal
Articles - Publications Submitted
After Final Report - Redisplay this page without
Reference Title, Journal, and Author Columns - Display this Page
in RIS Format
Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
---|---|---|---|---|---|---|
Journal Article | Interleukin-8, tumor necrosis factor-alpha, and lactoferrin in immunocompetent hosts with experimental and Brazilian children with acquired cryptosporidiosis. | AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | Alcantara CS, Yang C-H, Steiner TS, Barrett LJ, Lima AAM, Chappell CL, Okhuysen PC, White Jr AC, Guerrant RL | Alcantara CS, Yang C-H, Steiner TS, Barrett LJ, Lima AAM, Chappell CL, Okhuysen PC, White Jr AC, Guerrant RL. Interleukin-8, tumor necrosis factor-alpha, and lactoferrin in immunocompetent hosts with experimental and Brazilian children with acquired cryptosporidiosis. American Journal of Tropical Medicine and Hygiene 2003;68(3):325-328. |
R828035 (2001) R829180 (2002) |
|
Journal Article | Fecal Indole as a Biomarker of Sceptibility to Cryptosporidium Infection | None | Chappell C, Darkoh C, Schimmin L, Farhana N, Kim D, Okhuysen P, Hixson J | Chappell C, Darkoh C, Schimmin L, Farhana N, Kim D, Okhuysen P, Hixson J. Fecal Indole as a Biomarker of Sceptibility to Cryptosporidium Infection. INFECTION AND IMMUNITY 2016;84(8):2299-2306. |
R824759 (Final) R828035 (Final) |
|
Journal Article | Fecal antibodies to Cryptosporidium parvum in healthy volunteers. | INFECTION AND IMMUNITY | Dann SM, Okhuysen PC, Salameh BM, Dupont HL, Chappell CL | Dann SM, Okhuysen PC, Salameh BM, Dupont HL, Chappell CL. Fecal antibodies to Cryptosporidium parvum in healthy volunteers. Infection and Immunity 2000;68(9):5068-5074. |
R828035 (2000) |
|
Journal Article | Risk assessment for Cryptosporidium: a hierarchical Bayesian analysis of human dose response data. | WATER RESEARCH | Messner MJ, Chappell CL, Okhuysen PC | Messner MJ, Chappell CL, Okhuysen PC. Risk assessment for Cryptosporidium: a hierarchical Bayesian analysis of human dose response data. Water Research 2001;35(16):3934-3940. |
R828035 (2001) R829180 (2002) |
|
Journal Article | Cryptosporidium virulence determinants – are we there yet? | INTERNATIONAL JOURNAL FOR PARASITOLOGY | Okhuysen PC, Chappell CL | Okhuysen PC, Chappell CL. Cryptosporidium virulence determinants – are we there yet? International Journal for Parasitology 2002;32(5):517-525. |
R828035 (2001) R829180 (2002) R829180 (Final) |
|
Journal Article | Infectivity of a Cryptosporidium parvum isolate of cervine origin for healthy adults and interferon-gamma knockout mice. | JOURNAL OF INFECTIOUS DISEASES | Okhuysen PC, Rich SM, Chappell CL, Grimes KA, Widmer G, Feng X, Tzipori S | Okhuysen PC, Rich SM, Chappell CL, Grimes KA, Widmer G, Feng X, Tzipori S. Infectivity of a Cryptosporidium parvum isolate of cervine origin for healthy adults and interferon-gamma knockout mice. Journal of Infectious Diseases 2002;185(9):1320-1325. |
R828035 (2001) R829180 (2002) |
|
Journal Article | Molecular cloning and analysis of the Cryptosporidium parvum aminopeptidase N gene. | INTERNATIONAL JOURNAL OF PARASITOLOGY | Padda RS, Tsai A, Chappell CL, Okhuysen PC | Padda RS, Tsai A, Chappell CL, Okhuysen PC. Molecular cloning and analysis of the Cryptosporidium parvum aminopeptidase N gene. International Journal for Parasitology 2002;32(2):187-197. |
R828035 (2001) R829180 (2002) |
|
Journal Article | Transforming growth factor beta1 is expressed in the jejunum after experimental Cryptosporidium parvum infection in humans. | INFECTION AND IMMUNITY | Robinson P, Okhuysen PC, Chappell CL, Lewis DE, Shahab I, Lahoti S, White Jr AC | Robinson P, Okhuysen PC, Chappell CL, Lewis DE, Shahab I, Lahoti S, White Jr AC. Transforming growth factor beta1 is expressed in the jejunum after experimental Cryptosporidium parvum infection in humans. Infection and Immunity 2000;68(9):5405-5407. |
R828035 (2000) |
|
Journal Article | Expression of tumor necrosis factor alpha and interleukin 1beta in jejuna of volunteers after experimental challenge with Cryptosporidium parvum correlates with exposure but not with symptoms. | INFECTION AND IMMUNITY | Robinson P, Okhuysen PC, Chappell CL, Lewis DE, Shahab I, Janecki A, White Jr AC | Robinson P, Okhuysen PC, Chappell CL, Lewis DE, Shahab I, Janecki A, White Jr AC. Expression of tumor necrosis factor alpha and interleukin 1beta in jejuna of volunteers after experimental challenge with Cryptosporidium parvum correlates with exposure but not with symptoms. Infection and Immunity 2001;69(2):1172-1174. |
R828035 (2000) |
|
Journal Article | Cryptosporidium dose-response studies: variation between hosts. | RISK ANALYSIS | Teunis PFM, Chappell CL, Okhuysen PC | Teunis PFM, Chappell CL, Okhuysen PC. Cryptosporidium dose-response studies: variation between hosts. Risk Analysis 2002;22(3):475-485. |
R828035 (2001) R829180 (2002) |
|
Presentation | Cryptosporidium parvum volunteer study: infectivity and immunity. | None | Chappell CL, Okhuysen PC | Chappell CL, Okhuysen PC. Cryptosporidium parvum volunteer study: infectivity and immunity. Presented to the Australian Society of Microbiology, Perth, Australia, September 2001. |
R828035 (2001) |
not available |
Presentation | Evaluation of mice and enterocytes as surrogates for human Cryptosporidium parvum (genotype 2) infection. | None | Chappell CL, Marshall M, Widmer G, Okhuysen PC | Chappell CL, Marshall M, Widmer G, Okhuysen PC. Evaluation of mice and enterocytes as surrogates for human Cryptosporidium parvum (genotype 2) infection. Presented at the American Society of Parasitologists Meeting, San Juan, Puerto Rico, June 24-29, 2000. |
R828035 (2000) |
not available |
Presentation | Host immune factors in cryptosporidiosis: Environmental Protection Agency-defining susceptibility in microbial risk assessment: a dialogue. | None | Chappell CL, Okhuysen PC | Chappell CL, Okhuysen PC. Host immune factors in cryptosporidiosis: Environmental Protection Agency-defining susceptibility in microbial risk assessment: a dialogue. Presented at the George Washington University Center for Risk Science and Public Health, Washington, DC, June 26-27, 2001. |
R828035 (2001) |
not available |
Presentation | Cryptosporidium in healthy adults: infectivity, pathogenesis and the host-parasite relationship. | None | Chappell C | Chappell C. Cryptosporidium in healthy adults: infectivity, pathogenesis and the host-parasite relationship. Presented at the International Cryptosporidium from Molecules to Disease Conference, Fremantle, Australia, October 7-12, 2001. |
R828035 (2001) R829180 (2002) |
not available |
Presentation | Cryptosporidium in healthy humans: how infectious are they? | None | Chappell C | Chappell C. Cryptosporidium in healthy humans: how infectious are they? Presented at the 51st Annual Conference on Diseases in Nature Transmissible to Man, Austin, Texas, May 31-June 2, 2001. |
R828035 (2001) R829180 (2002) |
not available |
Presentation | Real-time quantitative PCR detection of intact and infectious Cryptosporidium parvum oocysts for water industry applications. | None | Di Giovanni DG, Chappell CL, LeChevallier MW | Di Giovanni DG, Chappell CL, LeChevallier MW. Real-time quantitative PCR detection of intact and infectious Cryptosporidium parvum oocysts for water industry applications. Presented at the American Society of Microbiology Meeting, Los Angeles, CA, May 21-25, 2000. |
R828035 (2000) |
not available |
Presentation | Sequential expression of IL-15, interferon gamma and IL-4 in cryptosporidiosis patients during immune reconstitution with HAART. | None | Okhuysen PC, Robinson P, Lewis DE, Shahab I, Lahoti S, Chappell CL, White Jr AC | Okhuysen PC, Robinson P, Lewis DE, Shahab I, Lahoti S, Chappell CL, White Jr AC. Sequential expression of IL-15, interferon gamma and IL-4 in cryptosporidiosis patients during immune reconstitution with HAART. Presented at the 7th Conference on Retroviruses, San Francisco, CA, January 30 - February 2, 2000. |
R828035 (2000) |
not available |
Presentation | Intestinal cytokine responses in cryptosporidiosis. | None | White Jr AC, Robinson P, Okhuysen PC, Lewis DE, Shahab I, Lahoti S, Chappell CL | White Jr AC, Robinson P, Okhuysen PC, Lewis DE, Shahab I, Lahoti S, Chappell CL. Intestinal cytokine responses in cryptosporidiosis. Presented at the Keystone Symposium on Innate and Acquired Immunity at Mucosal Surfaces, Taos, NM, January 18-23, 2000. |
R828035 (2000) |
not available |
Proceedings | Virulence determinants of Cryptosporidium-are we there yet? | None | Chappell CL, Okhuysen PC | Chappell CL, Okhuysen PC. Virulence determinants of Cryptosporidium-are we there yet? In: Proceedings of the VII International Coccidiosis Meeting, Australian Society of Parasitology, Palm Cove, Cairns, Australia, July 2001. |
R828035 (2001) R829180 (2002) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.