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Grantee Research Project Results

Publications Details for Grant Number R832733

Integrating Innovative Biomarkers of Environmentally Induced Disease for Children in Agricultural Communities

RFA: Early Indicators of Environmentally Induced Disease (2004)

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Abstract (1)
Journal Article (3)
Presentation (15)
Report (1)
Reference Type Reference Title Journal Author Citation Progress Report Year Document Sources
Abstract Organophosphate pesticide gene-interactions: lessons learned and future challenges. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS Griffith WC, Ramaprasad J, Coronado GC, Thompson B, Vigoren EM, Faustman EM Griffith WC, Ramaprasad J, Coronado GC, Thompson B, Vigoren EM, Faustman EM. Organophosphate pesticide gene-interactions: lessons learned and future challenges. Environmental and Molecular Mutagenesis 2009;50(7):539. R832733 (2009)
  • Other: Wiley Online-Issue Link
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Journal Article Glutamate cysteine ligase catalytic subunit promoter polymorphisms and associations with type 1 diabetes age-at-onset and GAD65 autoantibody levels. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES Bekris LM, Shephard C, Janer M, Graham J, McNeney B, Shin J, Zarghami M, Griffith W, Farin F, Kavanagh TJ, Lernmark A Bekris LM, Shephard C, Janer M, Graham J, McNeney B, Shin J, Zarghami M, Griffith W, Farin F, Kavanagh TJ, Lernmark A. Glutamate cysteine ligase catalytic subunit promoter polymorphisms and associations with type 1 diabetes age-at-onset and GAD65 autoantibody levels. Experimental and Clinical Endocrinology and Diabetes 2007;115(4):221-228. R831709 (2005)
R831709 (2007)
R831709 (Final)
R832733 (2007)
  • Abstract from PubMed
  • Abstract: Thieme Publishing-Abstract
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Journal Article Alteration of oral microbiome composition in children living with pesticide-exposed farm workers None Stanaway I, Wallace J, Hong S, WIlder C, Green F, Tsai J, Knight M, Workman T, Vigoren E, Smith M, Griffith W, Thompson B, Shojaie A, Faustman E Stanaway I, Wallace J, Hong S, WIlder C, Green F, Tsai J, Knight M, Workman T, Vigoren E, Smith M, Griffith W, Thompson B, Shojaie A, Faustman E. Alteration of oral microbiome composition in children living with pesticide-exposed farm workers. INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH 2023;248(114090). R832733 (Final)
R834514 (Final)
  • Full-text from PubMed
  • Full-text: Science Direct - Full Text HTML
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Journal Article A system-based approach to interpret dose- and time-dependent microarray data: quantitative integration of gene ontology analysis for risk assessment. TOXICOLOGICAL SCIENCES Yu X, Griffith WC, Hanspers K, Dillman III JF, Ong H, Vredevoogd MA, Faustman EM Yu X, Griffith WC, Hanspers K, Dillman III JF, Ong H, Vredevoogd MA, Faustman EM. A system-based approach to interpret dose-and time-dependent microarray data:quantitative integration of gene ontology analysis for risk assessment. Toxicological Sciences 2006;92(2):560-577. R831709 (2005)
R831709 (2006)
R831709 (2007)
R831709 (Final)
R831709C001 (2006)
R832733 (2007)
  • Abstract from PubMed
  • Full-text: Oxford Journals-Full Text HTML
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  • Abstract: Oxford Journals-Abstract
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  • Other: Oxford Journals-Full Text PDF
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Presentation Useful lessons for toxiogenomics using systems based approaches for dose and temporal response modeling. None Faustman EM, Yu X, Griffith WC, Robinson JF Faustman EM, Yu X, Griffith WC, Robinson JF. Useful lessons for toxiogenomics using systems based approaches for dose and temporal response modeling. Presented at the Society for Risk Analysis Annual Meeting, Boston, MA, December 7-10, 2008. R832733 (2009)
  • Abstract: Society for Risk Analysis-Abstract
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Presentation Pesticide exposure in children: evidence for a take home pathway. None Faustman EM Faustman EM. Pesticide exposure in children: evidence for a take home pathway. Presented at the 48th Annual Meeting of the Teratology Society, Monterey, CA, June 28-July 2, 2008. R832733 (2009)
  • Other: Teratology Society-Agenda Link
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Presentation Simulating the effects of polymorphisms and abundance of CYP-450 enzymes in metabolism of chlorpyrifos. None Griffith WC, Ramaprasad J, Faustman EM Griffith WC, Ramaprasad J, Faustman EM. Simulating the effects of polymorphisms and abundance of CYP-450 enzymes in metabolism of chlorpyrifos. Presented at the Society of Risk Analysis Annual Meeting, San Antonio, TX, December 9-12, 2007. R831709 (Final)
R832733 (2007)
not available
Presentation Using simple kinetic models to integrate experimental datasets: lessons learned with chlorpyrifos. None Griffith WC, Schumacher KM, Ramapradad J, Faustman EM Griffith WC, Schumacher KM, Ramapradad J, Faustman EM. Using simple kinetic models to integrate experimental datasets:lessons learned with chlorpyrifos. Presented at the Society for Risk Analysis Annual Meeting, Boston, MA, December 7-10, 2008. R831709 (Final)
R832733 (2009)
  • Abstract: Society for Risk Analysis-Abstract
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Presentation Value of information analysis integrating diverse information sources to estimate variability of genotypes and phenotypes of CYP450 enzymes in metabolism of chlorpyriphos. None Griffith WC, Vigoren EM, Faustman EM Griffith WC, Vigoren EM, Faustman EM. Value of information analysis integrating diverse information sources to estimate variability of genotypes and phenotypes of CYP450 enzymes in metabolism of chlorpyriphos. Presented at the Society of Toxicology Annual Meeting, Seattle, WA, March 15-19, 2008. R832733 (2009)
  • Other: Washington University-Conference Links
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Presentation Inhibition of acetylcholinesterase in a farmworker population exposed to organophosphate pesticides. None Griffith WC, Vigoren EM, Coronado GC, Thompson B, Faustman EM Griffith WC, Vigoren EM, Coronado GC, Thompson B, Faustman EM. Inhibition of acetylcholinesterase in a farmworker population exposed to organophosphate pesticides. Presented at the Society for Risk Analysis Annual Meeting, Baltimore, MD, December 6-9, 2009. R832733 (2009)
  • Abstract: Society for Risk Analysis-Meeting Abstracts Link
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Presentation Organophosphate pesticide residues in home environment dust of orchard workers. None Griffith WC, Coronado GC, Thompson B, Vigoren EM, Faustman EM Griffith WC, Coronado GC, Thompson B, Vigoren EM, Faustman EM. Organophosphate pesticide residues in home environment dust of orchard workers. Presented at the Society of Toxicology Annual Meeting, Baltimore, MD, March 2009. R832733 (2009)
  • Other: Washington University-Conference List
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Presentation Optimization of a protocol to isolate genomic material from buccal cells. None Guerrette Z, Yu X, Kim H, Hong S, Faustman EM Guerrette Z, Yu X, Kim H, Hong S, Faustman EM. Optimization of a protocol to isolate genomic material from buccal cells. Presented at the Society of Toxicology Annual Meeting, Baltimore, MD, March 15-19, 2009. R832733 (2009)
  • Other: Washington University-Conference Abstract List
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Presentation Urinary concentrations of dialkyl organophosphate metabolites in farmworkers and non-farmworkers and their children in a longitudinal cohort study. None Moreira EG, Coronado GC, Thompson B, Vigoren EM, Griffith WC, Faustman EM Moreira EG, Coronado GC, Thompson B, Vigoren EM, Griffith WC, Faustman EM. Urinary concentrations of dialkyl organophosphate metabolites in farmworkers and non-farmworkers and their children in a longitudinal cohort study. Presented at the Society of Toxicology Annual Meeting, Baltimore, MD, March 15-19, 2009. R831709 (Final)
R832733 (2009)
  • Other: University of Washington-Conference Abstract List
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Presentation Formal uncertainty analysis in the interpretation of organophosphate pesticide metabolite concentrations. None Vigoren EM, Griffith WC, Krogstad FTO, Coronado GD, Thompson B, Faustman EM Vigoren EM, Griffith WC, Krogstad FTO, Coronado GD, Thompson B, Faustman EM. Formal uncertainty analysis in the interpretation of organophosphate pesticide metabolite concentrations. Presented at the Society of Risk Analysis Annual Meeting. San Antonio, TX, December 2007 (abstract M5.65, p. 145). R832733 (2007)
not available
Presentation Integrative tools for improving our evaluation of accountability: lessons for pesticide biomarker studies. None Vigoren EM, Griffith WC, Krogstad F, Faustman EM Vigoren EM, Griffith WC, Krogstad F, Faustman EM. Integrative tools for improving our evaluation of accountability:lessons for pesticide biomarker studies. Presented at the Society for Risk Analysis Annual Meeting, Boston, MA, December 7-10, 2008. R831709 (Final)
R832733 (2009)
  • Other: University of Washington-Conference Abstract List
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Presentation Removing censorship bias from correlation estimates of datasets censored by limits of detection. None Vigoren EM, Krogstad F, Griffith WC, Faustman EM Vigoren EM, Krogstad F, Griffith WC, Faustman EM. Removing censorship bias from correlation estimates of datasets censored by limits of detection. Presented at the Society of Toxicology Annual Meeting, Seattle, WA, March 16-20, 2008. R832733 (2009)
  • Other: University of Washington-Conference Abstract List
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Presentation Longitudinal study of exposure to organophosphate pesticides comparing farmworker and nonfarmworker populations. None Vigoren EM, Griffith WC, Coronado GC, Thompson B, Faustman EM Vigoren EM, Griffith WC, Coronado GC, Thompson B, Faustman EM. Longitudinal study of exposure to organophosphate pesticides comparing farmworker and nonfarmworker populations. Presented at the Society for Risk Analysis Annual Meeting, Baltimore, MD, December 6-9, 2009. R832733 (2009)
  • Other: Society for Risk Analysis-Abstract
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Presentation Quantification of genomic data: value added assessment and application to toxicologically significant endpoints. None Vredevoogd MA, Yu X, Griffith WC, Faustman EM Vredevoogd MA, Yu X, Griffith WC, Faustman EM. Quantification of genomic data:value added assessment and application to toxicologically significant endpoints. Presented at the Society of Toxicology Annual Meeting, Charlotte, NC, March 2007. R832733 (2007)
not available
Presentation Critical molecular pathways of neurogenesis in chlorpyriphos response. None Vredevoogd M, Yu X, Hong S, Faustman EM Vredevoogd M, Yu X, Hong S, Faustman EM. Critical molecular pathways of neurogenesis in chlorpyriphos response. Presented at the Society of Toxicology Annual Meeting, Seattle, WA, March, 2008. R831709 (Final)
R832733 (2009)
  • Other: University of Washington-Conference Abstract List
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Report Principles for evaluating health risks in children associated with exposure to chemicals. None Louis GB, Damstra T, Diaz-Barriga F, Faustman E, Hass U, Kavlock R, Kimmel C, Kimmel G, Krishnan K, Luderer U, Sheldon L Louis GB, Damstra T, Diaz-Barriga F, Faustman E, Hass U, Kavlock R, Kimmel C, Kimmel G, Krishnan K, Luderer U, Sheldon L. Principles for evaluating health risks in children associated with exposure to chemicals. Environmental Health Criteria 237. Geneva, Switzerland: World Health Organization, 2006. R832733 (2007)
  • Other: World Health Organization-pdf
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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