Grantee Research Project Results
Publications Details for Grant Number R832733
Integrating Innovative Biomarkers of Environmentally Induced Disease for Children in Agricultural Communities
RFA:
Early Indicators of Environmentally Induced Disease (2004)
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Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
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Abstract | Organophosphate pesticide gene-interactions: lessons learned and future challenges. | ENVIRONMENTAL AND MOLECULAR MUTAGENESIS | Griffith WC, Ramaprasad J, Coronado GC, Thompson B, Vigoren EM, Faustman EM | Griffith WC, Ramaprasad J, Coronado GC, Thompson B, Vigoren EM, Faustman EM. Organophosphate pesticide gene-interactions: lessons learned and future challenges. Environmental and Molecular Mutagenesis 2009;50(7):539. |
R832733 (2009) |
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Journal Article | Glutamate cysteine ligase catalytic subunit promoter polymorphisms and associations with type 1 diabetes age-at-onset and GAD65 autoantibody levels. | EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES | Bekris LM, Shephard C, Janer M, Graham J, McNeney B, Shin J, Zarghami M, Griffith W, Farin F, Kavanagh TJ, Lernmark A | Bekris LM, Shephard C, Janer M, Graham J, McNeney B, Shin J, Zarghami M, Griffith W, Farin F, Kavanagh TJ, Lernmark A. Glutamate cysteine ligase catalytic subunit promoter polymorphisms and associations with type 1 diabetes age-at-onset and GAD65 autoantibody levels. Experimental and Clinical Endocrinology and Diabetes 2007;115(4):221-228. |
R831709 (2005) R831709 (2007) R832733 (2007) |
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Journal Article | Alteration of oral microbiome composition in children living with pesticide-exposed farm workers | None | Stanaway I, Wallace J, Hong S, WIlder C, Green F, Tsai J, Knight M, Workman T, Vigoren E, Smith M, Griffith W, Thompson B, Shojaie A, Faustman E | Stanaway I, Wallace J, Hong S, WIlder C, Green F, Tsai J, Knight M, Workman T, Vigoren E, Smith M, Griffith W, Thompson B, Shojaie A, Faustman E. Alteration of oral microbiome composition in children living with pesticide-exposed farm workers. INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH 2023;248(114090). |
R832733 (Final) R834514 (Final) |
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Journal Article | A system-based approach to interpret dose- and time-dependent microarray data: quantitative integration of gene ontology analysis for risk assessment. | TOXICOLOGICAL SCIENCES | Yu X, Griffith WC, Hanspers K, Dillman III JF, Ong H, Vredevoogd MA, Faustman EM | Yu X, Griffith WC, Hanspers K, Dillman III JF, Ong H, Vredevoogd MA, Faustman EM. A system-based approach to interpret dose-and time-dependent microarray data:quantitative integration of gene ontology analysis for risk assessment. Toxicological Sciences 2006;92(2):560-577. |
R831709 (2005) R831709 (2006) R831709 (2007) R831709C001 (2006) R832733 (2007) |
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Presentation | Useful lessons for toxiogenomics using systems based approaches for dose and temporal response modeling. | None | Faustman EM, Yu X, Griffith WC, Robinson JF | Faustman EM, Yu X, Griffith WC, Robinson JF. Useful lessons for toxiogenomics using systems based approaches for dose and temporal response modeling. Presented at the Society for Risk Analysis Annual Meeting, Boston, MA, December 7-10, 2008. |
R832733 (2009) |
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Presentation | Pesticide exposure in children: evidence for a take home pathway. | None | Faustman EM | Faustman EM. Pesticide exposure in children: evidence for a take home pathway. Presented at the 48th Annual Meeting of the Teratology Society, Monterey, CA, June 28-July 2, 2008. |
R832733 (2009) |
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Presentation | Simulating the effects of polymorphisms and abundance of CYP-450 enzymes in metabolism of chlorpyrifos. | None | Griffith WC, Ramaprasad J, Faustman EM | Griffith WC, Ramaprasad J, Faustman EM. Simulating the effects of polymorphisms and abundance of CYP-450 enzymes in metabolism of chlorpyrifos. Presented at the Society of Risk Analysis Annual Meeting, San Antonio, TX, December 9-12, 2007. |
R832733 (2007) |
not available |
Presentation | Using simple kinetic models to integrate experimental datasets: lessons learned with chlorpyrifos. | None | Griffith WC, Schumacher KM, Ramapradad J, Faustman EM | Griffith WC, Schumacher KM, Ramapradad J, Faustman EM. Using simple kinetic models to integrate experimental datasets:lessons learned with chlorpyrifos. Presented at the Society for Risk Analysis Annual Meeting, Boston, MA, December 7-10, 2008. |
R832733 (2009) |
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Presentation | Value of information analysis integrating diverse information sources to estimate variability of genotypes and phenotypes of CYP450 enzymes in metabolism of chlorpyriphos. | None | Griffith WC, Vigoren EM, Faustman EM | Griffith WC, Vigoren EM, Faustman EM. Value of information analysis integrating diverse information sources to estimate variability of genotypes and phenotypes of CYP450 enzymes in metabolism of chlorpyriphos. Presented at the Society of Toxicology Annual Meeting, Seattle, WA, March 15-19, 2008. |
R832733 (2009) |
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Presentation | Inhibition of acetylcholinesterase in a farmworker population exposed to organophosphate pesticides. | None | Griffith WC, Vigoren EM, Coronado GC, Thompson B, Faustman EM | Griffith WC, Vigoren EM, Coronado GC, Thompson B, Faustman EM. Inhibition of acetylcholinesterase in a farmworker population exposed to organophosphate pesticides. Presented at the Society for Risk Analysis Annual Meeting, Baltimore, MD, December 6-9, 2009. |
R832733 (2009) |
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Presentation | Organophosphate pesticide residues in home environment dust of orchard workers. | None | Griffith WC, Coronado GC, Thompson B, Vigoren EM, Faustman EM | Griffith WC, Coronado GC, Thompson B, Vigoren EM, Faustman EM. Organophosphate pesticide residues in home environment dust of orchard workers. Presented at the Society of Toxicology Annual Meeting, Baltimore, MD, March 2009. |
R832733 (2009) |
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Presentation | Optimization of a protocol to isolate genomic material from buccal cells. | None | Guerrette Z, Yu X, Kim H, Hong S, Faustman EM | Guerrette Z, Yu X, Kim H, Hong S, Faustman EM. Optimization of a protocol to isolate genomic material from buccal cells. Presented at the Society of Toxicology Annual Meeting, Baltimore, MD, March 15-19, 2009. |
R832733 (2009) |
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Presentation | Urinary concentrations of dialkyl organophosphate metabolites in farmworkers and non-farmworkers and their children in a longitudinal cohort study. | None | Moreira EG, Coronado GC, Thompson B, Vigoren EM, Griffith WC, Faustman EM | Moreira EG, Coronado GC, Thompson B, Vigoren EM, Griffith WC, Faustman EM. Urinary concentrations of dialkyl organophosphate metabolites in farmworkers and non-farmworkers and their children in a longitudinal cohort study. Presented at the Society of Toxicology Annual Meeting, Baltimore, MD, March 15-19, 2009. |
R832733 (2009) |
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Presentation | Formal uncertainty analysis in the interpretation of organophosphate pesticide metabolite concentrations. | None | Vigoren EM, Griffith WC, Krogstad FTO, Coronado GD, Thompson B, Faustman EM | Vigoren EM, Griffith WC, Krogstad FTO, Coronado GD, Thompson B, Faustman EM. Formal uncertainty analysis in the interpretation of organophosphate pesticide metabolite concentrations. Presented at the Society of Risk Analysis Annual Meeting. San Antonio, TX, December 2007 (abstract M5.65, p. 145). |
R832733 (2007) |
not available |
Presentation | Integrative tools for improving our evaluation of accountability: lessons for pesticide biomarker studies. | None | Vigoren EM, Griffith WC, Krogstad F, Faustman EM | Vigoren EM, Griffith WC, Krogstad F, Faustman EM. Integrative tools for improving our evaluation of accountability:lessons for pesticide biomarker studies. Presented at the Society for Risk Analysis Annual Meeting, Boston, MA, December 7-10, 2008. |
R832733 (2009) |
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Presentation | Removing censorship bias from correlation estimates of datasets censored by limits of detection. | None | Vigoren EM, Krogstad F, Griffith WC, Faustman EM | Vigoren EM, Krogstad F, Griffith WC, Faustman EM. Removing censorship bias from correlation estimates of datasets censored by limits of detection. Presented at the Society of Toxicology Annual Meeting, Seattle, WA, March 16-20, 2008. |
R832733 (2009) |
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Presentation | Longitudinal study of exposure to organophosphate pesticides comparing farmworker and nonfarmworker populations. | None | Vigoren EM, Griffith WC, Coronado GC, Thompson B, Faustman EM | Vigoren EM, Griffith WC, Coronado GC, Thompson B, Faustman EM. Longitudinal study of exposure to organophosphate pesticides comparing farmworker and nonfarmworker populations. Presented at the Society for Risk Analysis Annual Meeting, Baltimore, MD, December 6-9, 2009. |
R832733 (2009) |
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Presentation | Quantification of genomic data: value added assessment and application to toxicologically significant endpoints. | None | Vredevoogd MA, Yu X, Griffith WC, Faustman EM | Vredevoogd MA, Yu X, Griffith WC, Faustman EM. Quantification of genomic data:value added assessment and application to toxicologically significant endpoints. Presented at the Society of Toxicology Annual Meeting, Charlotte, NC, March 2007. |
R832733 (2007) |
not available |
Presentation | Critical molecular pathways of neurogenesis in chlorpyriphos response. | None | Vredevoogd M, Yu X, Hong S, Faustman EM | Vredevoogd M, Yu X, Hong S, Faustman EM. Critical molecular pathways of neurogenesis in chlorpyriphos response. Presented at the Society of Toxicology Annual Meeting, Seattle, WA, March, 2008. |
R832733 (2009) |
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Report | Principles for evaluating health risks in children associated with exposure to chemicals. | None | Louis GB, Damstra T, Diaz-Barriga F, Faustman E, Hass U, Kavlock R, Kimmel C, Kimmel G, Krishnan K, Luderer U, Sheldon L | Louis GB, Damstra T, Diaz-Barriga F, Faustman E, Hass U, Kavlock R, Kimmel C, Kimmel G, Krishnan K, Luderer U, Sheldon L. Principles for evaluating health risks in children associated with exposure to chemicals. Environmental Health Criteria 237. Geneva, Switzerland: World Health Organization, 2006. |
R832733 (2007) |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.