Grantee Research Project Results
Publications Details for Grant Number R832414C003
Project 3 -- Inhalation Exposure Assessment of San Joaquin Valley Aerosol
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Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
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Abstract | Exposure to ultrafine particles during allergic sensitization yields an altered lung epithelial structure. | None | Carosino CM, Harkema JR, Pinkerton KE | Carosino CM, Harkema JR, Pinkerton KE. Exposure to ultrafine particles during allergic sensitization yields an altered lung epithelial structure. The Toxicologist 2009;108(1):317 (Abstract No. 1531). |
R832414 (2010) R832414C003 (2009) R832414C003 (2010) |
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Abstract | Rapid uptake of inhaled solid phase ultrafine particles into the olfactory bulbs of mice. | None | Hopkins LE, Pinkerton KE | Hopkins LE, Pinkerton KE. Rapid uptake of inhaled solid phase ultrafine particles into the olfactory bulbs of mice. American Journal of Respiratory and Critical Care Medicine 2009;179(1):A5246. |
R832414 (2010) R832414C003 (2009) R832414C003 (2010) |
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Abstract | Murine pulmonary response following exposure to particulate matter of the California San Joaquin Valley | None | Plummer LE, Ham W, Kleeman MJ, Recendez JJ, Pinkerton KE | Plummer LE, Ham W, Kleeman MJ, Recendez JJ, Pinkerton KE. Murine pulmonary response following exposure to particulate matter of the California San Joaquin Valley. American Journal of Respiratory and Critical Care Medicine 2009;179(1):A3176. |
R832414 (2010) R832414C003 (2009) R832414C003 (2010) |
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Abstract | Species sensitivity to instillation-induced particle toxicity: a bioassay of particle dosimetry testing | None | Plummer LE, Carosino CM, Wegesser TC, Last JA, Pinkerton KE | Plummer LE, Carosino CM, Wegesser TC, Last JA, Pinkerton KE. Species sensitivity to instillation-induced particle toxicity:a bioassay of particle dosimetry testing. American Journal of Respiratory and Critical Care Medicine 2009;179(1):A1630. |
R832414 (2010) R832414C003 (2009) R832414C003 (2010) |
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Abstract | Platelet and systemic cytokine activation in mice exposed to concentrated ambient particulate matter | None | Wilson D W, Aung HH, Lame MW, Plummer L, Pinkerton KE, Ham W, Kleeman MW, Norris J, Tablin F | Wilson DW, Aung HH, Lame MW, Plummer L, Pinkerton KE, Ham W, Kleeman MW, Norris J, Tablin F. Platelet and systemic cytokine activation in mice exposed to concentrated ambient particulate matter. American Journal of Respiratory and Critical Care Medicine 2009;179(1):A3146. |
R832414 (2010) R832414C003 (2009) R832414C003 (2010) |
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Book Chapter | Airborne particles and structural remodeling of the lungs. | None | Madl AK, Carosino C, Pinkerton KE | Madl AK, Carosino CE, Pinkerton KE. Airborne particles and structural remodeling of the lungs. In: Gehr P, Muhlfeld C, Rothen-Rutishauser B, Blank F, eds. Particle-Lung Interactions, Second Edition. New York, NY: Informa Healthcare USA, Inc., 2009, Chapter 10, pp.167-193. |
R832414 (2010) R832414C003 (2010) R832414C003 (Final) |
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Book Chapter | Particle toxicities. | None | Madl AK, Carosino C, Pinkerton KE | Madl AK, Carosino C, Pinkerton KE. Particle toxicities. In: McQueen CA, ed. Comprehensive Toxicology, Second Edition. New York, NY :Elsevier, 2010, Chapter 8, pp. 421-451. |
R832414 (2010) R832414C003 (2010) R832414C003 (Final) |
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Book Chapter | Effects of nanoparticles on the pulmonary vasulature. | None | Plummer LE, Pinkerton KE, Madl AK, Wilson DW | Plummer LE, Pinkerton KE, Madl AK, Wilson DW. Effects of nanoparticles on the pulmonary vasulature. In: Cassee FR, Mills NL, Newby D, eds. Cardiovascular Effects of Inhaled Ultrafine and Nanosized Particles. Hoboken, NJ: John Wiley & Sons, 2011, Chapter 17, pp. 317-350. |
R832414 (2010) R832414 (Final) R832414C003 (Final) |
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Journal Article | Concordance between in vitro and in vivo dosimetry in the proinflammatory effects of low-toxicity, low-solubility particles: the key role of the proximal alveolar region. | INHALATION TOXICOLOGY | Donaldson K, Borm PJA, Oberdorster G, Pinkerton KE, Stone V, Tran CL | Donaldson K, Borm PJA, Oberdorster G, Pinkerton KE, Stone V, Tran CL. Concordance between in vitro and in vivo dosimetry in the proinflammatory effects of low-toxicity, low-solubility particles: the key role of the proximal alveolar region. Inhalation Toxicology 2008;20(1):53-62. |
R829215 (Final) R832414 (Final) R832414C003 (2008) R832414C003 (2009) R832414C003 (Final) |
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Journal Article | Size distribution of health-relevant trace elements in airborne particulate matter during a severe winter stagnation event: implications for epidemiology and inhalation exposure studies. | None | Ham WA, Herner JD, Green PG, Kleeman MJ | Ham WA, Herner JD, Green PG, Kleeman MJ. Size distribution of health-relevant trace elements in airborne particulate matter during a severe winter stagnation event: implications for epidemiology and inhalation exposure studies. Aerosol Science and Technology 2010;44(9):753-765. |
R832414 (2010) R832414C003 (2010) R832414C003 (Final) |
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Journal Article | Size distribution of particle-phase molecular markers during a severe winter pollution episode. | ENVIRONMENTAL SCIENCE & TECHNOLOGY | Kleeman MJ, Riddle SG, Jakober CA | Kleeman MJ, Riddle SG, Jakober CA. Size distribution of particle-phase molecular markers during a severe winter pollution episode. Environmental Science & Technology 2008;42(17):6469-6475. |
R832414 (2009) R832414C003 (2008) R832414C003 (2009) R832414C003 (Final) |
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Journal Article | Source apportionment of fine (PM1.8) and ultrafine (PM0.1) airborne particulate matter during a severe winter pollution episode. | None | Kleeman MJ, Riddle SG, Robert MA, Jakober CA, Fine PM, Hays MD, Schauer JJ, Hannigan MP | Kleeman MJ, Riddle SG, Robert MA, Jakober CA, Fine PM, Hays MD, Schauer JJ, Hannigan MP. Source apportionment of fine (PM1.8) and ultrafine (PM0.1) airborne particulate matter during a severe winter pollution episode. Environmental Science & Technology 2009;43(2):272-279. |
R832414 (2010) R832414C003 (2009) R832414C003 (2010) R832414C003 (Final) |
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Journal Article | Health effects of inhaled engineered and incidental nanoparticles | CRITICAL REVIEWS IN TOXICOLOGY | Madl AK, Pinkerton KE | Madl AK, Pinkerton KE. Health effects of inhaled engineered and incidental nanoparticles. Critical Reviews in Toxicology 2009;39(8):629-658. |
R829215 (Final) R831714 (2005) R832414 (2010) R832414C003 (2009) R832414C003 (2010) R832414C003 (Final) |
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Journal Article | Aerosolization system for experimental inhalation studies of carbon-based nanomaterials. | AEROSOL SCIENCE AND TECHNOLOGY | Madl AK, Teague SV, Qu Y, Masiel D, Evans JE, Guo T, Pinkerton KE | Madl AK, Teague SV, Qu Y, Masiel D, Evans JE, Guo T, Pinkerton KE. Aerosolization system for experimental inhalation studies of carbon-based nanomaterials. Aerosol Science and Technology 2012;46(1):94-107. |
R829215 (Final) R832414C003 (Final) |
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Journal Article | Airborne particles in the San Joaquin Valley may affect human health. | None | Ngo MA, Pinkerton KE, Freeland S, Geller M, Ham W, Cliff S, Hopkins LE, Kleeman MJ, Kodavanti UP, Meharg E, Plummer L, Recendez JJ, Schenker MB Sioutas C, Smiley-Jewell S, Haas C, Gutstein J, Wexler AS. | Ngo MA, Pinkerton KE, Freeland S, Geller M, Ham W, Cliff S, Hopkins LE, Kleeman MJ, Kodavanti UP, Meharg E, Plummer L, Recendez JJ, Schenker MB, Sioutas C, Smiley-Jewell S, Haas C, Gutstein J, Wexler AS. Airborne particles in the San Joaquin Valley may affect human health. California Agriculture 2010;64(1):12-16. |
R826246 (Final) R832413 (Final) R832413C001 (2010) R832413C001 (Final) R832414 (2010) R832414C003 (2010) R832414C003 (Final) |
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Journal Article | Central neuroplasticity and decreased heart rate variability after particulate matter exposure in mice. | None | Pham H, Bonham AC, Pinkerton KE, Chen C-Y | Pham H, Bonham AC, Pinkerton KE, Chen CY. Central neuroplasticity and decreased heart rate variability after particulate matter exposure in mice. Environmental Health Perspectives 2009;117(9):1448-1453. |
R831918 (Final) R832414 (2010) R832414C003 (2009) R832414C003 (2010) R832414C003 (Final) |
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Journal Article | Influence of season and location on pulmonary response to California's San Joaquin Valley airborne particulate matter. | JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A | Plummer LE, Ham W, Kleeman MJ, Wexler A, Pinkerton KE | Plummer LE, Ham W, Kleeman MJ, Wexler A, Pinkerton KE. Influence of season and location on pulmonary response to California's San Joaquin Valley airborne particulate matter. Journal of Toxicology and Environmental Health-Part A 2012;75(5):253-271. |
R832414 (Final) R832414C003 (Final) |
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Journal Article | Size-resolved source apportionment of airborne particle mass in a roadside environment. | ENVIRONMENTAL SCIENCE & TECHNOLOGY | Riddle SG, Robert MA, Jakober CA, Hannigan MP, Kleeman MJ | Riddle SG, Robert MA, Jakober CA, Hannigan MP, Kleeman MJ. Size-resolved source apportionment of airborne particle mass in a roadside environment. Environmental Science & Technology 2008;42(17):6580-6586. |
R832414 (2009) R832414 (Final) R832414C003 (2008) R832414C003 (2009) R832414C003 (Final) |
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Journal Article | Temperature-induced volatility of molecular markers in ambient airborne particulate matter. | None | Ruehl CR, Ham WA, Kleeman MJ | Ruehl CR, Ham WA, Kleeman MJ. Temperature-induced volatility of molecular markers in ambient airborne particulate matter. Atmospheric Chemistry and Physics 2011;11(1):67-76. |
R832414 (2010) R832414C003 (2010) |
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Journal Article | Pneumoconiosis from agricultural dust exposure among young California farmworkers. | ENVIRONMENTAL HEALTH PERSPECTIVES | Schenker MB, Pinkerton KE, Mitchell D, Vallyathan V, Elvine-Kreis B, Green FHY | Schenker MB, Pinkerton KE, Mitchell D, Vallyathan V, Elvine-Kreis B, Green FHY. Pneumoconiosis from agricultural dust exposure among young California farmworkers. Environmental Health Perspectives 2009;117(6):988-994. |
R826246 (Final) R832414 (2010) R832414C003 (2009) R832414C003 (2010) R832414C003 (Final) |
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Journal Article | Secondhand tobacco smoke exposure differentially alters nucleus tractus solitarius neurons at two different ages in developing non-human primates. | None | Sekizawa S-i, Joad JP, Pinkerton KE, Bonham AC | Sekizawa S-i, Joad JP, Pinkerton KE, Bonham AC. Secondhand tobacco smoke exposure differentially alters nucleus tractus solitarius neurons at two different ages in developing non-human primates. Toxicology and Applied Pharmacology 2010;242(2):199-208. |
R832414 (2010) R832414C003 (2010) R832414C003 (Final) |
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Journal Article | Acute pulmonary and systemic effects of inhaled coal fly ash in rats: comparison to ambient environmental particles. | TOXICOLOGICAL SCIENCES | Smith KR, Veranth JM, Kodavanti UP, Aust AE, Pinkerton KE | Smith KR, Veranth JM, Kodavanti UP, Aust AE, Pinkerton KE. Acute pulmonary and systemic effects of inhaled coal fly ash in rats: comparison to ambient environmental particles. Toxicological Sciences 2006;93(2):390-399. |
R829215 (Final) R832414 (Final) R832414C003 (2006) R832414C003 (2007) R832414C003 (2008) R832414C003 (Final) |
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Journal Article | California wildfires of 2008: coarse and fine particulate matter toxicity. | None | Wegesser TC, Pinkerton KE, Last JA | Wegesser TC, Pinkerton KE, Last JA. California wildfires of 2008: coarse and fine particulate matter toxicity. Environmental Health Perspectives 2009;117(6):893-897. |
R832414 (2010) R832414C003 (2009) R832414C003 (2010) R832414C003 (Final) |
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Journal Article | Exposure of mice to concentrated ambient particulate matter results in platelet and systemic cytokine activation. | INHALATION TOXICOLOGY | Wilson DW, Aung HH, Lame MW, Plummer L, Pinkerton KE, Ham W, Kleeman M, Norris JW, Tablin F | Wilson DW, Aung HH, Lame MW, Plummer L, Pinkerton KE, Ham W, Kleeman M, Norris JW, Tablin F. Exposure of mice to concentrated ambient particulate matter results in platelet and systemic cytokine activation. Inhalation Toxicology 2010;22(4):267-276. |
R832414 (2010) R832414 (Final) R832414C002 (Final) R832414C003 (2010) R832414C003 (Final) |
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Journal Article | Oxidative injury in the lungs of neonatal rats following short-term exposure to ultrafine iron and soot particles. | JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES | Zhong C-Y, Zhou Y-M, Smith KR, Kennedy IM, Chen C-Y, Aust AE, Pinkerton KE | Zhong C-Y, Zhou Y-M, Smith KR, Kennedy IM, Chen C-Y, Aust AE, Pinkerton KE. Oxidative injury in the lungs of neonatal rats following short-term exposure to ultrafine iron and soot particles. Journal of Toxicology and Environmental Health, Part A-Current Issues 2010;73(12):837-847. |
R829215 (Final) R832414 (2010) R832414C003 (2010) R832414C003 (Final) |
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Presentation | Time dependent decrease in heart rate variability to particulate matter exposure in mice. | None | Chen CY, Pinkerton KE, Bonham AC | Chen CY, Pinkerton KE, Bonham AC. Time dependent decrease in heart rate variability to particulate matter exposure in mice. Presented at the Annual Meeting for Experimental Biology, Washington, DC, May 2007. |
R832414C003 (2007) |
not available |
Presentation | Seasonal variation of airborne particle deposition efficiency in the human respiratory system. | None | Ham WA, Ruehl CR, Kleeman MJ | Ham WA, Ruehl CR, Kleeman MJ. Seasonal variation of airborne particle deposition efficiency in the human respiratory system. Presented at the American Association for Aerosol Research (AAAR) 29th Annual Conference, Portland, OR, October 25-29, 2010. |
R832414 (2010) R832414C003 (2010) |
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Report | Mechanisms of particulate matter toxicity in neonatal and young adult rat lungs. | None | Pinkerton KE, Zhou Y, Zhong C, Smith KR, Teague SV, Kennedy IM, Menache MG | Pinkerton KE, Zhou Y, Zhong C, Smith KR, Teague SV, Kennedy IM, Menache MG. Mechanisms of particulate matter toxicity in neonatal and young adult rat lungs. Boston, MA: Health Effects Institute Report 135, 2008, 68 pp. |
R832414 (Final) R832414C003 (2009) R832414C003 (Final) |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.