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Grantee Research Project Results

Publications Details for Grant Number R832144

Responses to Fresh Aerosol in Susceptible Subjects

RFA: The Role of Air Pollutants in Cardiovascular Disease (2003)

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Abstract (2)
Book Chapter (1)
Journal Article (9)
Presentation (5)
Reference Type Reference Title Journal Author Citation Progress Report Year Document Sources
Abstract Two Methods for Measurement of Acute Changes in Endothelial Function Following Diesel Exhaust Inhalation. None Gandhi S, Pettit AP, Ohman-Strickland P, Gow A, Zhang J, Lauer E, Kipen HM Gandhi S, Pettit AP, Ohman-Strickland P, Gow A, Zhang J, Lauer E, Kipen HM. Two methods for measurement of acute changes in endothelial function following diesel exhaust inhalation. American Journal of Respiratory and Critical Care Medicine 2009;179:A3164. R832144 (Final)
not available
Abstract Increase in Platelet Count but Absence of Platelet Activation Following 2 Hours of Diesel Exhaust. None Kipen HM, Gandhi S, Ohman-Strickland P, Choi H, Laskin DL, Rich D, Lauer E, Zhang J, Philipp CS Kipen HM, Gandhi S, Ohman-Strickland P, Choi H, Laskin DL, Rich D, Lauer E, Zhang J, Philipp CS. Increase in platelet count but absence of platelet activation following 2 hours of diesel exhaust. American Journal of Respiratory and Critical Care Medicine 2009;179:A6104. R832144 (Final)
not available
Book Chapter Inflammatory Cytokines and Lung Toxicity. None Laskin DL, Sunil VR, Laumbach RJ, Kipen HM Laskin DL, Sunil VR, Laumbach RJ, Kipen HM. Inflammatory Cytokines and Lung Toxicity. In: House RV, Descotes J, editors. Cytokines in Human Health: mmunotoxicology, Pathology, and Therapeutic Applications. Totowa, NJ: Humana Press, 2007, Chapter 6, pp. 83-112. R832144 (Final)
  • Full-text: Researchgate-Full Text PDF
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  • Abstract: Springer-Abstract
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Journal Article Report of prenatal maternal demoralization and material hardship and infant rhinorrhea and watery eyes None Conrad L, Rauh V, Hopener L, Acosta L, Perera F, Rundle A, Arteaga-Solis E, Miller R, Perzanowski M Conrad L, Rauh V, Hopener L, Acosta L, Perera F, Rundle A, Arteaga-Solis E, Miller R, Perzanowski M. Report of prenatal maternal demoralization and material hardship and infant rhinorrhea and watery eyes. Annals of Allergy Asthma & Immunology 2020;125(4):399. R832144 (Final)
R836154 (2019)
  • Abstract from PubMed
  • Abstract: Science Direct - Abstract HTML
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Journal Article Acute decreases in proteasome pathway activity after inhalation of fresh diesel exhaust or secondary organic aerosol. ENVIRONMENTAL HEALTH PERSPECTIVES Kipen HM, Gandhi S, Rich DQ, Ohman-Strickland P, Laumbach R, Fan ZH, Chen L, Laskin DL, Zhang J, Madura K Kipen HM, Gandhi S, Rich DQ, Ohman-Strickland P, Laumbach R, Fan ZH, Chen L, Laskin DL, Zhang J, Madura K. Acute decreases in proteasome pathway activity after inhalation of fresh diesel exhaust or secondary organic aerosol. Environmental Health Perspectives 2011;119(5):658-663. R832144 (Final)
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  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: EHP-Full Text HTML
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Journal Article Acute effects of motor vehicle traffic-related air pollution exposures on measures of oxidative stress in human airways. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES Laumbach RJ, Kipen HM Laumbach RJ, Kipen HM. Acute effects of motor vehicle traffic-related air pollution exposures on measures of oxidative stress in human airways. Annals of the New York Academy of Sciences 2010;1203(1):107-112. R832144 (Final)
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  • Abstract: ANYAS-Abstract
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Journal Article Acute changes in heart rate variability in subjects with diabetes following a highway traffic exposure. JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE Laumbach RJ, Rich DQ, Gandhi S, Amorosa L, Schneider S, Zhang J, Ohman-Strickland P, Gong J, Lelyanov O, Kipen HM Laumbach RJ, Rich DQ, Gandhi S, Amorosa L, Schneider S, Zhang J, Ohman-Strickland P, Gong J, Lelyanov O, Kipen HM. Acute changes in heart rate variability in subjects with diabetes following a highway traffic exposure. Journal of Occupational and Environmental Medicine 2010;52(3):324-331. R832144 (Final)
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  • Abstract: Ovid-Abstract
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Journal Article Quantification of 1-aminopyrene in human urine after a controlled exposure to diesel exhaust. JOURNAL OF ENVIRONMENTAL MONITORING Laumbach R, Tong J, Zhang L, Ohman-Strickland P, Stern A, Fiedler N, Kipen H, Kelly-McNeil K, Lioy P, Zhang J Laumbach R, Tong J, Zhang L, Ohman-Strickland P, Stern A, Fiedler N, Kipen H, Kelly-McNeil K, Lioy P, Zhang J. Quantification of 1-aminopyrene in human urine after a controlled exposure to diesel exhaust. Journal of Environmental Monitoring 2009;11(1):153-159. R832097 (Final)
R832144 (Final)
R832515 aka R832098 (2008)
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  • Abstract from PubMed
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  • Abstract: RSC-Abstract
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Journal Article Alteration of peripheral blood monocyte gene expression in humans following diesel exhaust inhalation. INHALATION TOXICOLOGY Pettit AP, Brooks A, Laumbach R, Fiedler N, Wang Q, Strickland PO, Madura K, Zhang J, Kipen HM Pettit AP, Brooks A, Laumbach R, Fiedler N, Wang Q, Strickland PO, Madura K, Zhang J, Kipen HM. Alteration of peripheral blood monocyte gene expression in humans following diesel exhaust inhalation. Inhalation Toxicology 2012;24(3):172-181. R832144 (Final)
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  • Abstract: Taylor&Francis-Abstract
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Journal Article Right heart pressure increases after acute increases in ambient particulate concentration. None Rich DQ, Freudenberger RS, Ohman-Strickland P, Cho Y, Kipen HM Rich DQ, Freudenberger RS, Ohman-Strickland P, Cho Y, Kipen HM. Right heart pressure increases after acute increases in ambient particulate concentration. Environmental Health Perspectives 2008;116(9):1167-1171. R832144 (2007)
R832144 (Final)
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  • Abstract from PubMed
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Journal Article Pulmonary effects of inhaled limonene ozone reaction products in elderly rats. None Sunil VR, Laumbach RJ, Patel KJ, Turpin BJ, Lim H-J, Kipen HM, Laskin JD, Laskin DL Sunil VR, Laumbach RJ, Patel KJ, Turpin BJ, Lim H-J, Kipen HM, Laskin JD, Laskin DL. Pulmonary effects of inhaled limonene ozone reaction products in elderly rats. Toxicology and Applied Pharmacology 2007;222(2):211-220. R832144 (2007)
R832144 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: Science Direct-Full Text HTML
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  • Other: Science Direct-Full Text PDF
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Journal Article Pulmonary effects of inhaled diesel exhaust in aged mice. TOXICOLOGY AND APPLIED PHARMACOLOGY Sunil VR, Patel KJ, Mainelis G, Turpin BJ, Ridgely S, Laumbach RJ, Kipen HM, Nazarenko Y, Veleeparambil M, Gow AJ, Laskin JD, Laskin DL Sunil VR, Patel KJ, Mainelis G, Turpin BJ, Ridgely S, Laumbach RJ, Kipen HM, Nazarenko Y, Veleeparambil M, Gow AJ, Laskin JD, Laskin DL. Pulmonary effects of inhaled diesel exhaust in aged mice. Toxicology and Applied Pharmacology 2009;241(3):283-293. R832144 (Final)
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  • Abstract from PubMed
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Presentation Triggering Acute Vascular Responses to Air Pollution: Endothelial and Platelet Responses to Fresh Aerosol Inhalation. None Kipen HM, Laumbach RL, Zhang J, Lioy P, Philipp C, Shindler D, Gandhi S, McNeil KK, Ohman-Strickland P, Laskin DL Kipen HM, Laumbach RL, Zhang J, Lioy P, Philipp C, Shindler D, Gandhi S, McNeil KK, Ohman-Strickland P, Laskin DL. Triggering acute vascular responses to air pollution: endothelial and platelet responses to fresh aerosol inhalation. Presented at the American Thoracic Society International Conference, San Francisco, CA, May 21, 2007. R832144 (Final)
not available
Presentation Acute platelet responses to ambient particulate matter. None Kipen HM, Gandhi S, Ohman-Strickland P, Philipp C Lauer E, Kipen HM, Gandhi S, Ohman-Strickland P, Philipp C, Rich DQ. Acute platelet responses to ambient particulate matter. Presented at the 21st International Society for Environmental Epidemiology (ISEE) Annual Conference, Dublin, Ireland, August 25-29, 2009. R832144 (Final)
not available
Presentation Triggering Myocardial Infarction: Acute Platelet Responses to Inhalation of Diesel Exhaust. None Howard Kipen, Robert Laumbach, Jim Zhang, Tina Fan, Paul Lioy, Claire Philipp, Petra Pham, Pamela Ohman-Strickland, Sampada Gandhi, Kathie Kelly McNeil and Debra Laskin Kipen H, Laumbach R, Zhang J, Fan T, Lioy P, Philipp C, Pham P, Ohman-Strickland P, Gandhi S, McNeil KK, Laskin D. Triggering myocardial infarction: acute platelet responses to inhalation of diesel exhaust. Presented at the Eleventh International Congress of Toxicology (ICT XI), Montreal, Canada, July 15-19, 2007. R832144 (Final)
not available
Presentation Glutathione-S-Transferase M1 and Effects of Diesel Exhaust on Heart Rate Variability in Healthy Humans. None Laumbach RJ, Lelyanov O, Gong J, Ohman-Strickland P, Kelly-McNeil K, Gandhi S, Wang Q, Zhang J, Fiedler N, Kipen HM Laumbach RJ, Lelyanov O, Gong J, Ohman-Strickland P, Kelly-McNeil K, Gandhi S, Wang Q, Zhang J, Fiedler N, Kipen HM. Glutathione-s-transferase m1 and effects of diesel exhaust on heart rate variability in healthy humans. Presented at the American Thoracic Society International Conference, Toronto, Canada, May 19, 2008. R832144 (Final)
not available
Presentation Urinary biomarkers of diesel exhaust exposure. None Zhang J, Zhang L, Fiedler N, Kipen H, Ohman-Strickland P, Laumbach R, Stern A, Lioy P Zhang J, Zhang L, Fiedler N, Kipen H, Ohman-Strickland P, Laumbach R, Stern A, Lioy P. Urinary biomarkers of diesel exhaust exposure. Presented at the 2007 Annual Meeting of the International Society of Exposure Analysis, Durham, NC, October 14-18, 2007. R832097 (2006)
R832144 (Final)
not available

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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