Grantee Research Project Results
Publications Details for Grant Number R831860
Diesel-induced Vascular Dysfunction: Role of Endothelin
RFA:
The Role of Air Pollutants in Cardiovascular Disease (2003)
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| Reference Type | Citation | Progress Report Year | Document Sources |
|---|---|---|---|
| Journal Article | Allahdadi KJ, Walker BR, Kanagy NL. Augmented endothelin vasoconstriction in intermittent hypoxia-induced hypertension. Hypertension 2005;45(4):705-709. |
R831860 (2008) R831860 (Final) |
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| Journal Article | Allahdadi KJ, Walker BR, Kanagy NL. ROK contribution to endothelin-mediated contraction in aorta and mesenteric arteries following intermittent hypoxia/hypercapnia in rats. American Journal of Physiology-Heart and Circulatory Physiology 2007;293(5):H2911-H2918. |
R831860 (2008) R831860 (Final) |
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| Journal Article | Allahdadi KJ, Duling LC, Walker BR, Kanagy NL. Eucapnic intermittent hypoxia augments endothelin-1 vasoconstriction in rats: role of PKCδ. American Journal of Physiology-Heart and Circulatory Physiology 2008;294(2):H920-H927. |
R831860 (2008) R831860 (Final) |
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| Journal Article | Allahdadi KJ, Cherng TW, Pai H, Silva AQ, Walker BR, Nelin LD, Kanagy NL. Endothelin type A receptor antagonist normalizes blood pressure in rats exposed to eucapnic intermittent hypoxia. American Journal of Physiology-Heart and Circulatory Physiology 2008;295(1):H434-H440. |
R831860 (2008) R831860 (Final) |
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| Journal Article | Bosc LVG, Resta T, Walker B and Kanagy NL. Mechanisms of intermittent hypoxia induced hypertension. Journal of Cellular and Molecular Medicine 2010;14(1-2):3-17, 2010. |
R831860 (Final) |
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| Journal Article | Cherng TW, Campen MJ, Knuckles TL, Gonzalez Bosc L, Kanagy NL. Impairment of coronary endothelial cell ETB receptor function after short-term inhalation exposure to whole diesel emissions. American Journal of Physiology. Regulatory, Integrative, and Comparative Physiology 2009;297(3):R640-R647. |
R831860 (2008) R831860 (Final) |
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| Journal Article | Cherng TW, Paffett ML, Jackson-Weaver O, Campen MJ, Walker BR, Kanagy NL. Mechanisms of diesel-induced endothelial nitric oxide synthase dysfunction in coronary arterioles. Environmental Health Perspectives 2011;119(1):98-103. |
R831860 (Final) |
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| Journal Article | Duling LC, Cherng TW, Griego JR, Perrine MF, Kanagy NL. Loss of α2B-adrenoceptors increases magnitude of hypertension following nitric oxide synthase inhibition. American Journal of Physiology-Heart and Circulatory Physiology 2006;291(5):H2403-H2408. |
R831860 (2008) R831860 (Final) |
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| Journal Article | Gomes da Silva AQ, Fontes MA, Kanagy NL. Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea. Brain Research 2010;1368:231-238. |
R831860 (Final) |
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| Journal Article | Kanagy NL. α2-adrenergic receptor signalling in hypertension. Clinical Science (London) 2005;109(5):431-437. |
R831860 (2008) R831860 (Final) |
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| Journal Article | Kanagy NL. Vascular effects of intermittent hypoxia. ILAR Journal 2009;50(3):282-288. |
R831860 (Final) |
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| Journal Article | Lund AK, Knuckles TL, Akata CO, Shohet R, McDonald JD, Gigliotti A, Seagrave JC, Campen MJ. Gasoline exhaust emissions induce vascular remodeling pathways involved in atherosclerosis. Toxicological Sciences 2007;95(2):485-494. |
CR831455 (Final) R830839 (2005) R830839 (Final) R831860 (2007) R831860 (Final) |
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| Journal Article | Snow JB, Kitzis V, Norton CE, Torres SN, Johnson KD, Kanagy NL, Walker BR, Resta TC. Differential effects of chronic hypoxia and intermittent hypocapnic and eucapnic hypoxia on pulmonary vasoreactivity. Journal of Applied Physiology 2008;104(1):110-118. |
R831860 (2008) R831860 (Final) |
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| Journal Article | Troncoso Brindeiro CM, da Silva AQ, Allahdadi KJ, Youngblood V, Kanagy NL. Reactive oxygen species contribute to sleep apnea-induced hypertension in rats. American Journal of Physiology-Heart and Circulatory Physiology 2007;293(5):H2971-H2976. |
R831860 (2008) R831860 (Final) |
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| Presentation | Cherng TW, Campen MJ, Kanagy NL. Altered coronary artery vasoreactivity in rats exposed to intermittent hypoxia/hypercapnia. Presented at the American Heart Association 60th Annual Fall Conference of the Council for High Blood Pressure Research, San Antonio, TX, October 4-7, 2006. |
R831860 (2006) |
not available |
| Presentation | Cherng TW, Campen MJ, Kanagy NL. Simulated sleep apnea augments endothelin activation by diesel exhaust exposure. Poster presented at Experimental Biology Annual Meeting, Washington, DC, April 28-May 2, 2007. |
R831860 (2007) |
not available |
| Presentation | Cherng TW, Campen MJ, Walker BR, Kanagy NL. Diesel exhaust exposure increases blood pressure, sympathetic activity and coronary artery endothelin sensitivity. Poster presented at the World Congress of the Microcirculatory Society, March 2007. |
R831860 (2007) |
not available |
| Presentation | Cherng TW, Campen MJ, Walker BR, Kanagy NL. Diesel exhaust exposure augments constrictor sensitivity to ET-1 that is ETB receptor mediated. Poster presented at the Society of Toxicology 48th Annual Meeting, Baltimore, MD, March 15-19, 2009. |
R831860 (2008) R831860 (Final) |
not available |
| Presentation | Cherng W, Campen MJ, Walker BR, Kanagy NL. Diesel exhaust exposure augments endothelium dependent endothelin constrictor sensitivity in rat coronary arteries. Presented at the Gordon Environmental Toxicology Conference, September 2008. |
R831860 (2008) R831860 (Final) |
not available |
| Presentation | Kanagy NL, Cherng T, Campen MJ. Diesel exhaust and sleep apnea augment coronary constrictor responsiveness and sympathetic nervous system activity. Presented at the U.S. Environmental Protection Agency, National Heart, Lung, and Blood Institute, and National Institute of Environmental Health Sciences Sponsored Meeting: The Role of Air Pollutants in Cardiovascular Disease, Research Triangle Park, NC, October 13-14, 2006. |
R831860 (2006) |
not available |
| Presentation | Seagrave JC, Kanagy NL, Campen MJ. Oxidation of LDL may mediate cardiovascular effects of air pollutants. Presented at the U.S. Environmental Protection Agency Conference on Cardiovascular Effects of Air Pollution, St. Louis, MO, 2004. |
R831860 (2005) |
not available |
| Presentation | Troncoso CM, Allahdadi KJ, Kanagy NL. Reactive oxygen species contribute to sleep apnea-induced hypertension in rats. Presented at the Annual Federation of American Societies for Experimental Biology Meeting, San Diego, CA, April 2-6, 2005. |
R831860 (2005) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.