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Grantee Research Project Results

Publications Details for Grant Number R827355C005

Mechanisms of Toxicity of Particulate Matter Using Transgenic Mouse Strains

RFA: Airborne Particulate Matter (PM) Centers (1999)

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Abstract (2)
Dissertation/Thesis (3)
Journal Article (1)
Presentation (2)
Reference Type Citation Progress Report Year Document Sources
Abstract Leaman SM, Vliet PA, Luchtel DL, Rosenfeld ME, Kavanagh TJ. Effects of particulate matter on glutamate cysteine ligase in RAW cells. Toxicological Sciences 2004;78(1S):1387. R827355 (Final)
R827355C005 (2004)
R827355C005 (Final)
not available
Abstract McConnachie L, Hudson FN, Ware CB, Fernandez C, Vliet PA, White CC, Kavanagh, TJ. Generation and characterization of a glutamate-cysteine ligase modifier subunit null mouse. Toxicological Sciences 2004;78(1S):2018. R827355 (Final)
R827355C005 (2004)
R827355C005 (Final)
not available
Dissertation/Thesis Fu C. Development of a transgenic mouse model to study the toxicity of particulate matter. Master's Thesis. Department of Environmental Health, University of Washington, Seattle, WA, 2001. R827355 (Final)
R827355C005 (2001)
R827355C005 (Final)
not available
Dissertation/Thesis Ghatpande P. Short-term effects of particulate matter on cardiopulmonary system of C57/BL6 and ApoE knockout mice. Master's Thesis. Department of Environmental Health, University of Washington, Seattle, WA, 2001. R827355 (Final)
R827355C005 (2001)
R827355C005 (Final)
not available
Dissertation/Thesis Smith LM. Effects and mechanisms of cardiopulmonary toxicity of Seattle particulate matter in the apolipoprotein E knockout transgenic mouse. Master's Thesis. Department of Environmental Health, University of Washington, Seattle, 2004. R827355 (Final)
R827355C005 (Final)
not available
Journal Article Corey LM, Baker C, Luchtel DL. Heart-rate variability in the apolipoprotein E knockout transgenic mouse following exposure to Seattle particulate matter. Journal of Toxicology and Environmental Health-Part A-Current Issues 2006;69(10):953-965. R827355 (Final)
R827355C005 (2004)
R827355C005 (Final)
  • Abstract from PubMed
  • Abstract: Taylor and Francis-Abstract
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Presentation Luchtel D. Mechanisms of toxicity of particulate matter using transgenic mouse strains. Presented at the Semiahoo Occupational Health and Safety Meeting, January 10, 2003. R827355C005 (2002)
not available
Presentation Luchtel D. Murine models of particulate matter toxicity. Presented at the PM Center Directors Meeting, Los Angeles, CA, July 9, 2002. R827355C005 (2002)
not available

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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