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Grantee Research Project Results

Publications Details for Grant Number R829399

Developmental Neurotoxicity in Offspring Induced by Combined Maternal Exposure of Rats to Nicotine and Chlorpyrifos

RFA: Children's Vulnerability to Toxic Substances in the Environment (2001)

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Journal Article (3)
Presentation (6)
Reference Type Citation Progress Report Year Document Sources
Journal Article Abdel-Rahman A, Dechkovskaia A, Mehta-Simmons H, Guan X, Khan W, Abou-Donia M. Increased expression of glial fibrillary acidic protein in cerebellum and hippocampus: differential effects on neonatal brain regional acetylcholinesterase following maternal exposure to combined chlorpyrifos and nicotine. Journal of Toxicology and Environmental Health, Part A 2003;66(21):2047-2066. R829399 (2003)
R829399 (2004)
R829399 (Final)
  • Abstract from PubMed
Journal Article Abdel-Rahman A, Dechkovskaia AM, Mehta-Simmons H, Sutton JM, Guan X, Khan WA, Abou-Donia MB. Maternal exposure to nicotine and chlorpyrifos, alone and in combination leads to persistently elevated expression of glial fibrilary acidic protein in the cerebellum of the offspring at late puberty. Archives of Toxicology 2004;78(8):467-476. R829399 (2004)
R829399 (Final)
  • Abstract from PubMed
Journal Article Abou-Donia MB, Abdel-Rahman A, Goldstein LB, Dechkovskaia AM, Shah DU, Bullman SL, Khan WA. Sensorimotor deficits and increased brain nicotinic acetylcholine receptors following exposure to chlorpyrifos and/or nicotine in rats. Archives of Toxicology 2003;77(8):452-458. R829399 (2002)
R829399 (2003)
R829399 (2004)
R829399 (Final)
  • Abstract from PubMed
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Presentation Abou-Donia MB, Dechkovskaia AM, Guan X, Abdel-Rahman A, Goldstein LB, Bullman SL, Khan WA. Developmental effects of maternal exposure to nicotine and chlorpyrifos, alone and in combination in rats. Presented at the 42nd Annual Meeting of the Society of Toxicology, Salt Lake City, UT, March 9-13, 2003. R829399 (2002)
R829399 (2003)
R829399 (2004)
R829399 (Final)
not available
Presentation Abou-Donia MB, Abdel-Rahman A, Dechkovskaia AM, Sutton JM, Guan X, Khan WA. Maternal exposure to nicotine via infusion during gestation produces neurobehavioral deficits and elevated expression of glial fibrillary acidic protein in the cerebellum in the offspring at puberty. Presented at the 43rd Annual Meeting of Society of Toxicology, Baltimore, MD, March 21-25, 2004. R829399 (2004)
R829399 (Final)
not available
Presentation Abou-Donia MB, Abdel-Rahman A, Dechkovskaia AM, Sutton JM, Guan X, Khan WA. Maternal exposure to nicotine via infusion during gestation produces neurobehavioral deficits and elevated expression of glial fibrillary acidic protein in the cerebellum in the offspring at puberty. To be presented at the 43rd Annual Meeting of the Society of Toxicology, Baltimore, MD, March 2004. R829399 (2003)
not available
Presentation Dechkovskaia AM, Abdel-Rahman A, Goldstein LB, Shah DU, Bullman SL, Khan WA, Abou-Donia MB. Cholinergic changes and neurobehavioral deficits following co-exposure with chlorpyrifos and nicotine in rats. Abstract presented at the 41st Annual Meeting of the Society of Toxicology, Nashville, TN, March 18-21, 2002. R829399 (2002)
R829399 (2003)
R829399 (2004)
R829399 (Final)
not available
Presentation Khan WA, Abdel-Rahman A, Dechkovskaia AM, Mehta-Simmons H, Sutton JM, Guan X, Abou-Donia MB. Elevated expression of glial fibrillary acidic protein in the cerebellum of the offspring at late puberty following maternal exposure to nicotine during gestation. Presented at the 43rd Annual Meeting of Society of Toxicology, Baltimore, MD, March 21-25, 2004. R829399 (2004)
R829399 (Final)
not available
Presentation Khan WA, Abdel-Rahman A, Dechkovskaia AM, Mehta-Simmons H, Sutton JM, Guan X, Abou-Donia MB. Elevated expression of glial fibrillary acidic protein in the cerebellum of the offspring at late puberty following maternal exposure to nicotine during gestation. To be presented at the 43rd Annual Meeting of the Society of Toxicology, Baltimore, MD, March 2004. R829399 (2003)
not available

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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