Grantee Research Project Results
Publications Details for Grant Number R827161
Mechanisms of Pb,Cd, As Interactions
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| Reference Type | Citation | Progress Report Year | Document Sources |
|---|---|---|---|
| Abstract | Fowler BA, Squibb KS, Akkerman M, Madden E. Comparative in vitro studies of cadmium and arsenic-induced apoptosis in renal tubule epithelial cells. The Toxicologist 2000. |
R827161 (1999) R827161 (2000) |
not available |
| Abstract | Fowler BA, Akkerman M, Madden EF. A comparison of cytotoxicity in HK-2 and primary human renal proximal tubule cells following in vitro exposure to arsenite (As3+), cadmium (Cd2+) or the combination of arsenite plus cadmium. The Toxicologist 2001;60(1):1489. |
R827161 (2000) R827161 (2001) |
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| Abstract | Madden EF, Akkerman M, Tuggle T, Fowler BA. A comparison of the cytotoxicity and the stress protein response in rat NRK-52 and human HK-2 cell lines following in vitro exposure to arsenite, cadmium or the combination of arsenite plus cadmium. The Toxicologist 2001;60(1):1488. |
R827161 (2000) R827161 (2001) |
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| Abstract | Madden EF, Fowler BA, Akkerman M. Comparative regulation of NRK-52E and HK-2 kidney cell death pathways in vitro by arsenic (As3+), cadmium (Cd2+) and As x Cd combinations. The Toxicologist 2002;66(1-S):181. |
R827161 (2001) |
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| Abstract | Wang G, Whittaker MH, Lipsky M, Chen X, Fowler BA. Six month drinking water study to establish a LOEL for cadmium toxicity. The Toxicologist 2002;66(1-S):996. |
R827161 (2001) |
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| Abstract | Wang G, Fowler B. Roles of biomarkers in evaluating interactions among mixtures of lead, cadmium and arsenic. TOXICOLOGY AND APPLIED PHARMACOLOGY 2008;233(1):92-99. |
R827161 (2001) |
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| Abstract | Whittaker MH, Lipsky M, Wang G, Chen X, Fowler BA. Chronic dose response study of lead toxicity in rats: assignment of a lowest observed effect level in a drinking water study. The Toxicologist 2002;66(1-S):146. |
R827161 (2001) |
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| Journal Article | Madden EF, Akkerman M, Fowler BA. A comparison of 60, 70, and 90 kDa stress protein expression in normal rat NRK-52 and human HK-2 kidney cell lines following in vitro exposure to arsenite and cadmium alone or in combination. Journal of Biochemistry and Molecular Toxicology 2002;16(1):24-32. |
R827161 (2001) |
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| Paper | Madden EF, Akkerman M, Fowler BA. Interactive effects of exposure to arsenic, cadmium and lead on regulation of NRK52E and HK-2 kidney cell death pathways in vitro. |
R827161 (2001) |
not available |
| Presentation | Fowler BA. Mechanisms of lead, cadmium and arsenic interactions. Presented at the University of Maryland/United States Food and Drug Administration Joint Institute for Food Safety and Applied Nutrition Colloquium, Laurel, MD, June 8, 2001. |
R827161 (2001) |
not available |
| Presentation | Fowler BA, Akkerman M, Madden EF. A comparison of cytotoxicity in HK-2 and primary human renal proximal tubule cells following in vitro exposure to arsenite (AS3+), cadmium (CD2+) or the combination of arsenite plus cadmium. Presented at the 40th Annual Meeting of the Society of Toxicology San Francisco, CA, March 25-29, 2001. |
R827161 (2001) |
not available |
| Presentation | Fowler BA. Mechanisms of lead, cadmium and arsenic interactions. Presented at the Catholic University de Louvain, Symposium in Honor of the Retirement of Professor Robert Lauwerys, Brussels, Belgium, October 6, 2001. |
R827161 (2001) |
not available |
| Presentation | Fowler BA, Madden EF, Akkerman M. Mechanisms of Pb, Cd and As interactions. Presented at the Third International Meeting on Molecular Mechanisms of Metal Toxicity and Carcinogenicity, Stintino, Italy, September 2-5, 2001. |
R827161 (2001) |
not available |
| Presentation | Madden EF, Akkerman M, Tuggle TR, Fowler BA. A comparison of the cytotoxicity and the stress protein response in rat NRK-52 and human HK-2 cell lines following in vitro exposure to arsenite, cadmium or the combination of arsenite plus cadmium. Presented at the 40th Annual Meeting of the Society of Toxicology, San Francisco, CA, March 25-29, 2001. |
R827161 (2001) |
not available |
| Presentation | Madden EF. Comparative in vitro mechanisms of combined metal toxicity to renal proximal tubule cells and the role of the stress protein response. Presented to the Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, MD, 2001. |
R827161 (2001) |
not available |
| Presentation | Madden EF, Fowler BA, Akkerman M. Comparative regulation of NRK-52E and HK-2 kidney cell death pathways in vitro by arsenic (As3+), Cadmium(Cd2+) and As x Cd combinations. Presented at the 41st Annual Meeting of the Society of Toxicology, Nashville, TN, March 17-21, 2002. |
R827161 (2001) |
not available |
| Presentation | Wang G, Whittaker MH, Lipsky M, Chen X, Fowler BA. Six month drinking water study to establish a LOEL for cadmium toxicity. Presented at the 41st Annual Meeting of the Society of Toxicology, Nashville, TN, March 17-21, 2002. |
R827161 (2001) |
not available |
| Presentation | Whittaker MH, Lipsky M, Wang G, Chen X, Fowler BA. Chronic dose response study of lead toxicity in rats: assignment of a lowest observed effect level in a drinking water study. Presented at the 41st Annual Meeting of the Society of Toxicology, Nashville, TN, March 17-21, 2002. |
R827161 (2001) |
not available |
| Proceedings | Fowler BA, Akkerman M, Madden EF, Squibb KS, Lipsky MM. Arsenic (As) and cadmium (Cd) interactions on cellular viability in rat and human kidney cells in vitro. In: Proceedings of the 6th International Symposium on Metal Ions in Biology and Medicine, San Juan, Puerto Rico, May 7-10, 2000. |
R827161 (1999) R827161 (2000) |
not available |
| Proceedings | Fowler BA, Akkerman M, Madden EF, Gallicchio L, Whittaker M. Comparative in vitro studies of arsenic and cadmium interactions on cellular viability and stress response in rat renal tubule epithelial cells. In: Proceedings of the 21st Annual Meeting of the American College of Toxicology, San Diego, CA, November 12-15, 2000. |
R827161 (2000) |
not available |
| Proceedings | Fowler BA, Squibb KS, Akkerman M, Madden E. Comparative in vitro studies of cadmium and arsenic-induced apoptosis in renal tubule epithelial cells. In: Proceedings of the 39th Annual Meeting of the Society of Toxicology, March 19-23, 2000. |
R827161 (2000) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.