Grantee Research Project Results
Publications Details for Grant Number R834677C150
Mutagenicity of Stereochemical Configurations of 1,3-Butadiene Epoxy Metabolites in Human Cells
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| Reference Type | Citation | Progress Report Year | Document Sources |
|---|---|---|---|
| Abstract | Meng Q, Hackfeld LC, Hodge RP, Walker VE. Comparison of mutagenicity of stereochemical forms of 1,2,3,4-diepoxybutane at HPRT and TK loci in human cells and rodents. Toxicology 2003;191(1):36-37. |
R834677C150 (Final) |
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| Journal Article | Meng Q, Hackfeld LC, Hodge RP, Walker VE. Comparison of mutagenicity of stereochemical forms of 1,2,3,4-diepoxybutane at HPRT and TK loci in human cells. Environmental and Molecular Mutagenesis 2003;41(36 Supplement):77. |
R834677C150 (Final) |
not available |
| Journal Article | Meng Q, Redetzke DL, Hackfeld LC, Hodge RP, Walker DM, Walker VE. Mutagenicity of stereochemical configurations of 1,2-epoxybutene and 1,2:3,4-diepoxybutane in human lymphoblastoid cells. Chemico-Biological Interactions 2007;166(1-3):207-218. |
R834677C150 (Final) |
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| Presentation | Meng Q, Walker VE. Mutagenicity of stereochemical configurations of 1,3-butadiene epoxy metabolites in human cells. Presented at the Health Effects Institute Annual Conference, Seattle, WA, April 28-30, 2002. |
R834677C150 (Final) |
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| Presentation | Meng Q, Hackfeld LC, Hodge RP, Long L, Walker VE. Mutagenicity of stereochemical forms of 1,2,3,4-diepoxybutane at HPRT and TK loci in human cells. Presented at the Health Effects Institute Annual Conference, Boulder, CO, May 4-6, 2003. |
R834677C150 (Final) |
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| Presentation | Meng Q, Hackfeld LC, Hodge RP, Redtzeke DL. Comparison of mutagenicity of stereoisomers of 1,2,3,4-diepoxybutane and 3,4-epoxybutene in primary mouse lymphocytes or in TK6 cells. Presented at the Health Effects Institute Annual Conference, Boston, MA, May 2-4, 2004. |
R834677C150 (Final) |
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| Presentation | Meng Q, Hackfeld LC, Hodge RP, Wisse L. (2R,3S)-3-Epoxybutane-1,2-diol is significantly more cytotoxic and mutagenic than other stereoisomers of 3-epoxybutane-1,2-diol in TK6 cells. Presented at the Health Effects Institute Annual Conference, Baltimore, MD, April 17-19, 2005. |
R834677C150 (Final) |
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| Presentation | Meng Q, Hackfeld LC, Hodge RP, Tu M. Comparison of cytotoxicity and mutagenicity of stereoisomers of 3-epoxybutane-1,2-diol at low concentrations in TK6 cells. Presented at the Health Effects Institute Annual Conference, Chicago, IL, April 15-17, 2007. |
R834677C150 (Final) |
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| Report | Meng RQ, Hackfeld LC, Hodge RP, Wisse LA, Redetzke DL, Walker VE. Mutagenicity of stereochemical configurations of 1,3-butadiene epoxy metabolites in human cells. Boston, MA: Health Effects Institute, July 8, 2010, Report No. 150. |
R834677C150 (Final) |
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.