Grantee Research Project Results
Journal Publications Details for Grant Number R835168
Toxicity Screening with Zebrafish Assay
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| Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
|---|---|---|---|---|---|---|
| Journal Article | Phenotype anchoring in zebrafish reveals a potential role for matrix metalloproteinases (MMPs) in tamoxifen's effects on skin epithelium. | TOXICOLOGY AND APPLIED PHARMACOLOGY | Bugel SM, Wehmas LC, La Du JK, Tanguay RL | Bugel SM, Wehmas LC, La Du JK, Tanguay RL. Phenotype anchoring in zebrafish reveals a potential role for matrix metalloproteinases (MMPs) in tamoxifen's effects on skin epithelium. Toxicology and Applied Pharmacology 2016;296:31-41. |
R835168 (Final) |
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| Journal Article | Advancements in zebrafish applications for 21st century toxicology. | PHARMACOLOGY & THERAPEUTICS | Garcia GR, Noyes PD, Tanguay RL | Garcia GR, Noyes PD, Tanguay RL. Advancements in zebrafish applications for 21st century toxicology. Pharmacology & Therapeutics 2016;161:11-21. |
R835168 (Final) |
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| Journal Article | High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes. | ARCHIVES OF TOXICOLOGY | Reif DM, Truong L, Mandrell D, Marvel S, Zhang G, Tanguay RL | Reif DM, Truong L, Mandrell D, Marvel S, Zhang G, Tanguay RL. High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes. Archives of Toxicology 2016;90(6):1459-1570. |
R835168 (Final) |
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| Journal Article | Optimizing multi-dimensional high throughput screening using zebrafish. | REPRODUCTIVE TOXICOLOGY | Truong L, Bugel SM, Chlebowski A, Usenko CY, Simonich MT, Simonich SLM, Tanguay RL | Truong L, Bugel SM, Chlebowski A, Usenko CY, Simonich MT, Simonich SLM, Tanguay RL. Optimizing multi-dimensional high throughput screening using zebrafish. Reproductive Toxicology 2016;65:139-147. |
R835168 (Final) R835796 (2017) |
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| Journal Article | A new statistical approach to characterize chemical-elicited behavioral effects in high-throughput studies using zebrafish. | PLOS ONE | Zhang GZ, Truong L, Tanguay RL, Reif DM | Zhang G, Truong L, Tanguay RL, Reif DM. A new statistical approach to characterize chemical-elicited behavioral effects in high-throughput studies using zebrafish. PLoS One 2017;12(1):e0169408 (16 pp.). |
R835168 (Final) R835796 (2017) |
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| Journal Article | Aggregate entropy scoring for quantifying activity across endpoints with irregular correlation structure. | REPRODUCTIVE TOXICOLOGY | Zhang G, Marvel S, Truong L, Tanguay RL, Reif DM | Zhang G, Marvel S, Truong L, Tanguay RL, Reif DM. Aggregate entropy scoring for quantifying activity across endpoints with irregular correlation structure. Reproductive Toxicology 2016;62:92-99. |
R835168 (Final) R835796 (2017) R835802 (2015) R835802 (2016) R835802 (2017) R835802 (2018) R835802C003 (2015) |
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| Journal Article | A data-driven weighting scheme for multivariate phenotypic endpoints recapitulates zebrafish developmental cascades. | None | Zhang G, Roell KR, Truong L, Tanguay RL, Reif DM | Zhang G, Roell KR, Truong L, Tanguay RL, Reif DM. A data-driven weighting scheme for multivariate phenotypic endpoints recapitulates zebrafish developmental cascades. Toxicology and Applied Pharmacology 2017;314:109-117. |
R835168 (Final) |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.