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Grantee Research Project Results

Journal Publications Details for Grant Number R825358

Improving Methods for Identifying Noncancer Risks Application of Cell Kinetic Models for Methylmercury Risk Assessment

RFA: Exploratory Research - Human Health (1996)

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Journal Article (5)
Reference Type Reference Title Journal Author Citation Progress Report Year Document Sources
Journal Article Methylmercury distribution in the pregnant rat and embryo during early midbrain organogenesis. TERATOLOGY Lewandowski TA, Pierce CH, Pingree SD, Hong S, Faustman EM Lewandowski TA, Pierce CH, Pingree SD, Hong S, Faustman EM. Methylmercury distribution in the pregnant rat and embryo during early midbrain organogenesis. Teratology 2002;66(5):235-241. R825358 (Final)
R826886 (2000)
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Journal Article Changes in cell cycle kinetics and cell number in the rat midbrain during organogenesis. None Lewandowski TA, Ponce RA, Charleston JS, Hong S, Faustman EM Lewandowski TA, Ponce RA, Charleston JS, Hong S, Faustman EM. Effect of methylmercury on midbrain cell proliferation during organogenesis: potential cross-species differences and implications for risk assessment. Toxicological Sciences 2003;75(1):124-133. R825358 (Final)
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Journal Article p21WAF1/CIP1 inhibits cell cycle progression but not G2/M-phase transition following methylmercury exposure. TOXICOLOGY AND APPLIED PHARMACOLOGY Mendoza MAC, Ponce RA, Ou YC, Faustman EM Mendoza MAC, Ponce RA, Ou YC, Faustman EM. p21WAF1/CIP1 inhibits cell cycle progression but not G2/M-phase transition following methylmercury exposure. Toxicology and Applied Pharmacology 2002;178(2):117-125. R825358 (Final)
R826886 (2000)
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Journal Article Induction of the cell cycle regulatory gene p21 (Waf1, Cip1) following methylmercury exposure in vitro and in vivo. TOXICOLOGY AND APPLIED PHARMACOLOGY Ou YC, Thompson SA, Ponce RA, Schroeder J, Kavanagh TJ, Faustman EM Ou YC, Thompson SA, Ponce RA, Schroeder J, Kavanagh TJ, Faustman EM. Induction of the cell cycle regulatory gene p21 (Waf1, Cip1) following methylmercury exposure in vitro and in vivo. Toxicology and Applied Pharmacology 1999;157(3):203-212. R825358 (Final)
R826886 (2000)
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Journal Article The role of intracellular glutathione in methylmercury-induced toxicity in embryonic neuronal cells. NEUROTOXICOLOGY Ou YC, White CC, Krejsa CM, Ponce RA, Kavanagh TJ, Faustman EM Ou YC, White CC, Krejsa CM, Ponce RA, Kavanagh TJ, Faustman EM. The role of intracellular glutathione in methylmercury-induced toxicity in embryonic neuronal cells. NeuroToxicology 1999;20(5):793-804. R825358 (Final)
R826886 (2000)
  • Abstract from PubMed

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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