Grantee Research Project Results
Journal Publications Details for Grant Number R831847
Estrogen Elicited Gene Expression Network Elucidation in the Rat Uterus
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Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
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Journal Article | Cell adhesion on polyelectrolyte multilayer coated polydimethylsiloxane surfaces with varying topographies. | TISSUE ENGINEERING | Kidambi S, Udpa N, Schroeder SA, Findlan R, Lee I, Chan C | Kidambi S, Udpa N, Schroeder SA, Findlan R, Lee I, Chan C. Cell adhesion on polyelectrolyte multilayer coated polydimethylsiloxane surfaces with varying topographies. Tissue Engineering 2007;13(8):2105-2117. |
R831847 (Final) |
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Journal Article | Patterned co-culture of primary hepatocytes and fibroblasts using polyelectrolyte multilayer templates. | MACROMOLECULAR BIOSCIENCE | Kidambi S, Sheng L, Yarmush ML, Toner M, Lee I, Chan C | Kidambi S, Sheng L, Yarmush ML, Toner M, Lee I, Chan C. Patterned co-culture of primary hepatocytes and fibroblasts using polyelectrolyte multilayer templates. Macromolecular Bioscience 2007;7(3):344-353. |
R831847 (Final) |
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Journal Article | o,p'-DDT elicits PXR/CAR-, not ER-, mediated responses in the immature, ovariectomized rat liver. | TOXICOLOGICAL SCIENCES | Kiyosawa N, Kwekel JC, Burgoon LD, Williams KJ, Tashiro C, Chittim B, Zacharewski TR | Kiyosawa N, Kwekel JC, Burgoon LD, Williams KJ, Tashiro C, Chittim B, Zacharewski TR. o,p'-DDT elicits PXR/CAR-, not ER-, mediated responses in the immature, ovariectomized rat liver. Toxicological Sciences 2008;101(2)350-363. |
R831847 (Final) |
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Journal Article | A cross-species analysis of the rodent uterotrophic program: elucidation of conserved responses and targets of estrogen signaling. | PHYSIOLOGICAL GENOMICS | Kwekel JC, Burgoon LD, Burt JW, Harkema JR, Zacharewski TR | Kwekel JC, Burgoon LD, Burt JW, Harkema JR, Zacharewski TR. A cross-species analysis of the rodent uterotrophic program: elucidation of conserved responses and targets of estrogen signaling. Physiological Genomics 2005;23(3):327-342. |
R831847 (2006) R831847 (Final) |
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Journal Article | o-p'-DDT-mediated uterotrophy and gene expression in immature C57BL/6 mice and Sprague-Dawley rats | TOXICOLOGY AND APPLIED PHARMACOLOGY | Kwekel J, Forgacs A, Williams K, Zacharewski T | Kwekel J, Forgacs A, Williams K, Zacharewski T. o-p'-DDT-mediated uterotrophy and gene expression in immature C57BL/6 mice and Sprague-Dawley rats. TOXICOLOGY AND APPLIED PHARMACOLOGY 2013;273(3):532-541 |
R831847 (Final) |
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Journal Article | Using a state-space model with hidden variables to infer transcription factor activities. | BIOINFORMATICS | Li Z, Shaw SM, Yedwabnick MJ, Chan C | Li Z, Shaw SM, Yedwabnick MJ, Chan C. Using a state-space model with hidden variables to infer transcription factor activities. Bioinformatics 2006;22(6):747-754. |
R831847 (Final) |
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Journal Article | A three stage integrative pathway search (TIPS©) framework to identify toxicity relevant genes and pathways. | BMC BIOINFORMATICS | Li Z, Srivastava S, Mittal S, Yang X, Sheng L, Chan C | Li Z, Srivastava S, Mittal S, Yang X, Sheng L, Chan C. A three stage integrative pathway search (TIPS©) framework to identify toxicity relevant genes and pathways. BMC Bioinformatics 2007;8:202. |
R831847 (Final) |
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Journal Article | A hierarchical approach employing metabolic and gene expression profiles to identify the pathways that confer cytotoxicity in HepG2 cells. | BMC SYSTEMS BIOLOGY | Li Z, Srivastava S, Yang X, Mittal S, Norton P, Resau J, Haab B, Chan C | Li Z, Srivastava S, Yang X, Mittal S, Norton P, Resau J, Haab B, Chan C. A hierarchical approach employing metabolic and gene expression profiles to identify the pathways that confer cytotoxicity in HepG2 cells. BMC Systems Biology 2007;1:21. |
R831847 (Final) |
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Journal Article | Using dynamic gene module map analysis to identify targets that modulate free fatty acid induced cytotoxicity. | BIOTECHNOLOGY PROGRESS | Li Z, Srivastava S, Findlan R, Chan C | Li Z, Srivastava S, Findlan R, Chan C. Using dynamic gene module map analysis to identify targets that modulate free fatty acid induced cytotoxicity. Biotechnology Progress 2008;24(1):29-37. |
R831847 (Final) |
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Journal Article | Involvement of astroglial ceramide in palmitic acid-induced Alzheimer-like changes in primary neurons. | EUROPEAN JOURNAL OF NEUROSCIENCE | Patil S, Melrose J, Chan C | Patil S, Melrose J, Chan C. Involvement of astroglial ceramide in palmitic acid-induced Alzheimer-like changes in primary neurons. European Journal of Neuroscience 2007;26(8):2131-2141. |
R831847 (Final) |
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Journal Article | Hydrogen peroxide and hydroxyl radicals mediate palmitate-induced cytotoxicity to hepatoma cells: relation to mitochondrial permeability transition. | FREE RADICAL RESEARCH | Srivastava S, Chan C | Srivastava S, Chan C. Hydrogen peroxide and hydroxyl radicals mediate palmitate-induced cytotoxicity to hepatoma cells:relation to mitochondrial permeability transition. Free Radical Research 2007;41(1):38-49. |
R831847 (Final) |
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Journal Article | Identification of genes that regulate multiple cellular processes/responses in the context of lipotoxicity to hepatoma cells. | BMC GENOMICS | Srivastava S, Li Z, Yang X, Yedwabnick M, Shaw S, Chan C | Srivastava S, Li Z, Yang X, Yedwabnick M, Shaw S, Chan C. Identification of genes that regulate multiple cellular processes/responses in the context of lipotoxicity to hepatoma cells. BMC Genomics 2007;8:364. |
R831847 (Final) |
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Journal Article | Application of metabolic flux analysis to identify the mechanisms of free fatty acid toxicity to human hepatoma cell line. | BIOTECHNOLOGY AND BIOENGINEERING | Srivastava S, Chan C | Srivastava S, Chan C. Application of metabolic flux analysis to identify the mechanisms of free fatty acid toxicity to human hepatoma cell line. Biotechnology and Bioengineering 2008;99(2):399-410. |
R831847 (Final) |
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Journal Article | Repression of PKR mediates palmitate-induced apoptosis in HepG2 cells through regulation of Bcl-2. | CELL RESEARCH | Yang X, Chan C | Yang X, Chan C. Repression of PKR mediates palmitate-induced apoptosis in HepG2 cells through regulation of Bcl-2. Cell Research 2009;19(4):469-486. |
R831847 (Final) |
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.