Grantee Research Project Results
Journal Publications Details for Grant Number R826301
Species-Specific Endocrine Disruption: PCB- and PAH-Induced Estrogenic Effects
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| Reference Type | Citation | Progress Report Year | Document Sources |
|---|---|---|---|
| Journal Article | Celius T, Matthews JB, Giesy JP, Zacharewski TR. Quantification of rainbow trout (Oncorhynchus mykiss) zona radiata and vitellogenin mRNA levels using real-time PCR after in vivo treatment with estradiol-17 beta or alpha-zearalenol. Journal of Steroid Biochemistry and Molecular Biology 2000;75(2-3):109-119. |
R826301 (2000) R826301 (Final) |
not available |
| Journal Article | Fertuck KC, Matthews JB, Zacharewski TR. Hydroxylated benzo[a]pyrene metabolites are responsible for in vitro estrogen receptor-mediated gene expression induced by benzo[a]pyrene, but do not elicit uterotrophic effects in vivo. Toxicological Sciences 2001;59(2):231-240. |
R826301 (2001) R826301 (Final) |
not available |
| Journal Article | Fertuck KC, Kumar S, Sikka HC, Matthews JB, Zacharewski TR. Interaction of PAH-related compounds with the α and β isoforms of estrogen receptor. Toxicology Letters 2001;121(3):167-177. |
R826192 (Final) R826301 (2001) R826301 (Final) |
not available |
| Journal Article | Huang YW, Matthews JB, Fertuck KC, Zacharewski TR. Use of Xenopus laevis as a model for investigating in vitro and in vivo endocrine disruption in amphibians. Environmental Toxicology and Chemistry 2005;24(8):2002-2009 |
R826301 (Final) |
not available |
| Journal Article | Matthews JB, Twomey K, Zacharewski TR. In vitro and in vivo interactions of bisphenol A and its metabolite, bisphenol A glucuronide, with estrogen receptors alpha and beta. Chemical Research in Toxicology 2001;14(2):149-157 |
R826301 (Final) |
not available |
| Journal Article | Matthews JB, Clemons JH, Zacharewski TR. Reciprocal mutagenesis between human α(L349, M528) and rainbow trout (M317, I496) estrogen receptor residues demonstrates their importance in ligand binding and gene expression at different temperatures. Molecular and Cellular Endocrinology 2001;183(1-2):127-139 |
R826301 (2001) R826301 (Final) |
not available |
| Journal Article | Matthews JB, Fertuck KC, Celius T, Huang YW, Fong CJ, Zacharewski TR. Ability of structurally diverse natural products and synthetic chemicals to induce gene expression mediated by estrogen receptors from various species. Journal of Steroid Biochemistry and Molecular Biology 2002;82(2-3):181-194 |
R826301 (Final) |
not available |
| Journal Article | Matthews J, Zacharewski T. Differential binding affinities of PCBs, HO-PCBs, and aroclors with recombinant human, rainbow trout (Onchorhynkiss mykiss), and green anole (Anolis carolinensis) estrogen receptors, using a semi-high throughput competitive binding assay. Toxicological Sciences 2000;53(2):326-339. |
R826301 (1999) R826301 (Final) |
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| Journal Article | Matthews J, Celius T, Halgren R, Zacharewski T. Differential estrogen receptor binding of estrogenic substances: a species comparison. Journal of Steroid Biochemistry and Molecular Biology 2000;74(4):223-234. |
R826301 (2001) |
not available |
| Journal Article | Rosen G, O'Bryant E, Matthews J, Zacharewski T, Wade J. Distribution of androgen receptor mRNA expression and immunoreactivity in the brain of the green anole lizard. Journal of Neuroendocrinology 2002;14(1):19-28. |
R826301 (2001) R826301 (Final) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.